MODIFICATION OF MENDELIAN RATIOS Flashcards

1
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
most frequently encountered allele in a population, arbitrarily considered as normal.

A

WILD-TYPE ALLELE

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2
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
Modification of genetic sequence

A

MUTATION

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3
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
Mutation that brough about diminished functionality of the gene

A

LOSS OF FUNCTION MUTATION

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4
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
Eventual loss of function of a gene due to mutation

A

NULL ALLELE

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5
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
Increased activity of a gene due to mutation

A

GAIN OF FUNCTION MUTATION

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6
Q

ALLELES ALTER PHENOTYPES IN DIFFERENT WAYS:
Mutation in a gene that does not necessarily altered its activity

A

NEUTRAL MUTATION

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7
Q

GENETICISTS USE A VARIETY OF SYMBOL FOR ALLELES:
Lowercase and italicized (dd)

A

RECESSIVE ALLELE

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8
Q

GENETICISTS USE A VARIETY OF SYMBOL FOR ALLELES:
Uppercase and italicized (DD)

A

DOMINANT ALLELE

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9
Q

In a population of organisms, the presence of three or more alleles of the same gene.

A

MULTIPLE ALLELES

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10
Q

The ABO Blood Group was discovered by

A

KARL LANDSTEINER

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11
Q

The simplest case of multiple alleles is that which three alternative alleles of one gene exist

A

THE ABO BLOOD GROUP

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12
Q

A rare variant of the ABO antigen system in which affected individuals do not have A or B antigens and thus appear to have blood type O, even though their genotype may carry unexpressed alleles for the A and/or B antigens.

A

THE BOMBAY PHENOTYPE

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13
Q

Genetic mutation which might lead to death

Genes function primarily for the expression/production of substances essential to life,

A

LETHAL ALLELES

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14
Q

LETHAL ALLELES:
The lethal mutation is present (mutation that leads to total non-functionality of the gene) but there is another allele that may compensate.

A

HETEROZYGOUS RECESSIVE LETHAL ALLELE

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15
Q

LETHAL ALLELE:
Lethal indeed

A

HOMOZYGOUS RECESSIVE LETHAL ALLELE

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16
Q

LETHAL ALLELE
Inheritance of even just one copy is lethal

A

DOMINANT LETHAL ALLELE

17
Q

It is defined as the tendency for alleles close together on the same chromosome to be transmitted together as an intact unit through meiosis.

A

GENETIC LINKAGE

18
Q

PHENOTYPES ARE OFTEN AFFECTED BY MORE THAN ONE GENE:
The non-reciprocal interaction between non-allelic genes such that one gene influences or interferes with the expression of another gene, leading to a specific phenotype.

A

EPISTASIS

19
Q

PHENOTYPES ARE OFTEN AFFECTED BY MORE THAN ONE GENE:
Other cases of gene interaction yield novel, or new, phenotypes in the F2 generation, in addition to producing modified dihybrid ratios.

A

NOVEL PHENOTYPES

20
Q
A