Modern Developments in Microbiology Flashcards

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1
Q

Poliomyelitis can grow in cultures

A

Enders
Weller
Robbins

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2
Q

Yellow Fever

A

Theiler

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3
Q

Genetic structure and replication of bacteriophage

A

Delbruck
Hershey
Luria

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4
Q

Tyhpus -> Lice

A

Nicolle

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5
Q

HIV

A

Sinoussi
Luc Montagnier

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6
Q

Helicobacter pylori

A

Marshall
Warren

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7
Q

Tuberculosis

A

Koch

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8
Q

Diphtheria

A

Von Behring

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9
Q

Genetic recombination of bacteria

A

Lederberg

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10
Q

Retroviral oncogenes

A

Bishop
Varmus

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11
Q

Viruses can cause animal cancer

A

Huggins
Roux

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12
Q

Malaria

A

Ross

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13
Q

Penicillin

A

Fleming
Florey
Chain

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14
Q

Sulfa drugs

A

Domagk

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15
Q

Streptomycin

A

Waksman

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16
Q

Human papilloviruses

A

Hausen

17
Q

Malariotherapy for late stage of syphilis

A

Wagner-Jeuregg

18
Q

Prions

A

Prusiner

19
Q

Mosquito - Malaria

A

Laveran

20
Q

First prototype electron microscope capable of four-hundred-power magnification
400x

A

Knoll
Ruska

21
Q

One gene-one enzyme hypothesis

A

Beadle
Tatum

22
Q

Genetic mutation “arises in the absence” of selection

A

Luria
Delbruck

23
Q

Streptomycin produced by two strains of actinomycete, Streptomyces griseus

A

Waksman

24
Q

DNA is the substance that causes bacterial transformation
It was first described in Griffith’s experiment of 1928.

A

Avery
MacLeod
McCarty

25
Q

DNA model, which is now accepted as the first correct model of the double-helix

A

Watson
Crick

26
Q

Radioactively labelled hybridisation probes

A

Joseph Gall
Mary Lou Pardue

27
Q

More user-friendly fluorophores replaced the radioactive labels leading to the development of

A

Fluorescence in situ hybridisation (FISH)

28
Q

They are DNA or RNA fragments that can bind to complementary sequences in the microbial chromosome

A

Hybridisation probes

29
Q

Ribosomal genes that led to the first scientifically based tree of life

A

Carl Woese

30
Q

small 16S ribosomal RNA subunit for:
18S rRNA subunit for:

A

bacteria
eukaryotic organisms

31
Q

Eradicates smallpox

A

World Health Organization

32
Q

HIV as causative agent of AIDS

A

Luc Montaigner
Robert Gallo

33
Q

Polymerase chain reaction (PCR)
- enables a target stretch of DNA to be copied thousands or millions of times.

A

Kary Mullis