mod 9

Question 1

fatty acid synthesis occurs in _____

Answer 1

cytosol

Question 2

three stages of fatty acid synthesis

Answer 2

1. shuttle acetyl coa from mitochondria to cytosol
2. activate acetyl coa to form malonyl coa
3. synthesize palmitate in a five-step elongation cycle

Question 3

_______ carries acetyl groups from mitochondria to the cytosol

Answer 3

Citrate

• acetyl CoA combines w oxaloacetate to form citrate and leaves mitochondria
• ATP citrate lyase cleaves it back into acetyl coa and oxaloacetate once back in cytosol - acetyl coa in cytosol at expense of 1 atp
• oxaloacetate reduced to malate using malate reductase