Mod 23- Part 1 Flashcards
This is known as the major excretory organ
Kidney
This is an excretory organ that is for temporary storage reservoir for the urine
Urinary Bladder
These transport urine from the kidneys to the bladder
Ureters
This transports urine out of the body
Urethra
This is the function of the Kidney, to remove _____, _______ wastes and excess ____ form the blood
Toxins
Metabolic
Ions
The kidneys regulate _____ volume, _______ composition and __
Blood
Chemical
pH
During starvation, the kidney is know to produce _____ through gluconeogenesis
Glucose
The Kidney also functions as an endocrine organ releasing ____ to regulate the blood pressure and kidney function
Renin
The kidney also acts as a endocrine organ when it releases _____ to regulate the production of RBCs
Erthropoietin
The kidneys are located ________ to the rest of the organs and are in the _____ lumbar region
Retroperiotenal
Superior
The ______ kidney is lower than the _____ because of the Liver
Right
Left
The renal hilum leads to the renal _____
Sinus
This is a layer of supportive tissue that anchors the outer layer of dense fibrous connective tissue
Renal Fascia
This is a layer of supportive tissue in the Kidney that is known to be the fatty cushion
Peritoneal fat capsule
This is a supportive layer of the kidney that prevents the spread of infection to the kidney
Fibrous capsule
This is a granular superficial layer
Renal Cortex
This is known as the cone shaped part of the kidney that is made of pyramids separated by _________
Renal medullary
Renal Columns
This is the tip of the medullary pyramid that releases urine into the minor calyx
Papillia
This is the funnel shaped tube within the renal sinus
Renal pelvis
These are the major channels for the renal pelvis that collect urine from the minor calyces and empty urine into the pelvis
Major calyces
These are the structural and functional units that form urine
Nephrons
What are the two parts of the nephrons
Golmerulus
Renel Tubule
These are found in Nephrons and are a tuft of cappillaries
Glomerulus
These are found in the Nephrons and begin as a sup-shaped glomerular or ______ capsule surrounding the glomerulus
Renel Tubule
Bowmans
This is known as the Glomerulus and its glomerular capsule
Renal Corpuscle
The glomerular capsule has two layers, what are they?
Parietal
Visceral
This is a glomerular layer that is simple squamous epithelium
Parietal
This is the glomerular layer that is inside and has branching epithelial podocytes
Visceral
These allow filtrate to pass into the capsular space of the renal tubule
Filtration slits
These are cuboidal cells with dense mircovilli and large mitochondria , they are confined to the cortex
Proximal convoluted tubule (PCT)
This has ascending and descending limbs
Loop of Henle
This segment is usually in the descending limb
Thin
This segment is found in the ascending limb
Thick
This segment of the renal tubule has function more in secretion than absorption and it is confined to the cortex
Distal Convoluted tubule
These receive filtrates from many nephrons, they fuse together to deliver urine through papillae into minor calyces
Collecting Ducts
This is a cell type of the collecting ducts that function in maintaining the acid-base balance
Intercalated discs
THis is a cell type of the collecting ducts that function in the maintaining of the bodies water and salt balance
Principal cells
These are 85% of almost all of the nephrons, almost all in the cortex
Cortical Nephrons
These nephrons are long loops of Henley that deeply invade the medulla are are important in the production of concentrated urine
Juxtamedullary nephrons
These are in the capillary beds and go from afferent to efferent, they specialize in filtration
Golmerulus
These are in nephron capillary beds that are low pressure, porous capillaries that are adapted for absorption and arise from efferent atrieoles and are in the cortex but empty into venules
Peritbular capillaries
These are long vessels of the nephron capillary bed parallel to long loops of Henle, that arise from efferent arteioles and function in the concentration of urine
Vasa Recta
These are one per nephron and are important in regulating the filtrate and blood pressure
Juxtaglomerular Apparatus (JGA)
These are cells that are enlarged smooth muscle cells of the arteriole, they contain renin and act as mechanorecptors that sense blood pressure
Granular Cells
These cells are tall closely packed cells of ascending limbs that act as chemorecptors that sense NaCl content of filtrate
Macula Densa
These cells are interconnected with gap junctions that may pass signals between macula densa and granular cells
Extraglomerular mesangial cells
This is the porous membrane in-between the blood and capsular space
Filtration Membrane
This is in the Filtration Membrane and is the covering of the glomerular capillaries
Fenestrated endothelium
This is the part of the Filtration Membrane that has foot like projections coming from the glomerular capsule
Visceral Membrane
This is part of the Filtration Membrane and is a gel like _____ _____ fused to the laminae
Basement membrane
The Filtration Membrane always allows the passage of ____ and other _____
Water
Solutes
The filtration of the Filtration Membrane prevents the entrance of _____
RBCs
These are in the Filtration Membrane and are known to engulf and degrade macromolecules and can contract to change the entire surface area
Glomerular Mesangial cells
The kidneys filter the bodies entire plasma volume __ times per day
60
What does the kidney not filter?
Protein
Urine is only __% of total filtrate
1
What are the three mechanics for urine formation?
Glomerular Filtration
Tubular Reabsorption
Tubular Secretion
This is a passive mechanical process driven by hydrostatic pressure or NFP, it is very efficient because its membrane is very permeable and has large surface area
Glomerular Filtration
This is responsible for filtrate formation and is determined by glomerular hydrostatic pressure and the two opposing forces of colloid osmotic pressure and capsular hydrostatic pressure
Net Filtration Pressure
This is the volume of filtrate formed per minute by the kidneys (120-125 min)
Glomerular Filtration Rate
What two controls are the GFR controlled by?
Intrinsic and Extrinsic
This is a control of the GFR that maintains nearly constant GFR when MAP is in the range of 80-180 and act locally in the Kidneys
Intrinsic control
THis is a control of the GFR when the nervous and endocrine mechanics that maintain blood pressure but affect kidney function
Extrinsic Control
What are the two intrinsic renal auto regulation?
Myogenic
Tubuloglomerular feedback mechanism
In this myogenic control, when the blood pressure raises, there is a ______ of afferent arterioles
constriction
In this myogenic control, when the blood pressure lowers, there is a _____ of afferent arterioles
dilation
This intrinsic control of the GFR flows-dependent mechanism directed by the macula densa cells
Tubuloglomerular feedback mechanism
If the NaCl concentration is high, the macula densa cells cause _____ of the afferent arterioles and a reduction in the GFR. The opposite happens when NaCL is low
constriction
The extrinsic controls of the GFR are controlled by the _______ nervous system
Sympathetic
Under normal conditions are rest, the renel blood vessels are ______ and the renal autoregulations prevail
dialated
Under extreme stress, _____ is released by the sympathetic nervous system and ______ is released by the adrenal medulla both casuing constriction of afferent arterioles inhibiting filtration and triggering reinin
Norepinephrine
Epinephrine