Mock Questions Flashcards
What is the dose of Naproxen for Rheumatoid Arthritis?
0.5 - 1g in divided doses
What countries can have their prescriptions dispensed in the UK?
Austria
Belgium; Bulgaria
Croatia; Cyprus; Czech Republic
Denmark
Estonia
Finland; France
Germany; Greece
Hungary
Iceland; Republic of Ireland; Italy
Latvia; Liechtenstein; Lithuania; Luxembourg
Malta
The Netherlands
Norway
Poland; Portugal
Romania
Slovakia; Slovenia; Spain; Sweden
Switzerland
A 10-year-old comes in with a sprained ankle. There is mild swelling and he does not seem to be in discomfort. What is the most appropriate option for him?
Using an ice pack
A 12-year-old comes in with a sprained ankle. There is moderate swelling and he does seem to be in discomfort. What is the most appropriate option for him?
Ibuprofen
A patient has started Simvastatin 40mg
His drug history: Bezefibrate, Amlodipine, Ramipril. What adjustment needs to be made?
Reduce dose of Simvastatin to 10mg due to bezafibrate.
If bezafibrate wasn’t there, reduce simvastatin to 20mg
What dose adjustment do you need to make to simvastatin due to interactions? 6
Bezfibrate or Ciprofibrate = 10mg daily
Amlodipine, Amiodarone, Ranolazine = 20mg daily
CYP inhbitors = reduce dose ->
Verapamil/Diltiazem (inhibitors) =20mg daily
Bempedoic acid (with ezetimbe) = 20mg daily
Severe hypercholesterolaemia and at high risk of cardiovascular complications = 40mg daily
lomitapide or ticagrelor = 40mg daily
When taking Carbimazole what causes sore throat and mouth ulcers
Agranulocytosis - lowered white blood cell count
and Neutropenia - low conc of neutrophils
What are contributing factors of hypoglycaemia
Taking too much insulin or diabetes medication.
Not eating enough.
Postponing or skipping a meal or snack.
Increasing exercise or physical activity without eating more or adjusting your medications.
Drinking alcohol
What is the age limit of OTC Naproxen for period pains
15-50
A patient has been taking pseudoephedrine for the past 3 days for a cold and flu. They present at the hospital with a fast heart rate, bp of 170/90 and headache.
Drug history:
Amlodipine - started last week
Phenelzine - taken off last week
Bempedoic acid - dose increase last week
Which could have caused the hospital admission?
There is a SEVERE interaction between
MAOIs e.g. Phenelzine, Isocarboxazid or Tranylcypromine and Pseudoephedrine
It’s predicted to cause hypertensive crisis during and up to 14 days after stopping MAOIs
symptoms = hypertension, palpitation, headache, dizziness, visual disturbances, SOB and malaise
List of notifiable disease in the UK that start with A, B, C, D
Acute encephalitis
Acute infectious hepatitis
Acute meningitis
Acute poliomyelitis
Anthrax
Botulism
Brucellosis
Cholera
COVID-19
Diphtheria
List of notifiable dieases that start with E, F, H, I
Enteric fever (typhoid or paratyphoid fever)
Food poisoning
Haemolytic uraemic syndrome (HUS)
Infectious bloody diarrhoea
Invasive group A streptococcal disease
List of notifiable diseases that start with L, M, P
Legionnaires’ disease
Leprosy
Malaria
Measles
Meningococcal septicaemia
Monkeypox
Mumps
Plague
List of notifiable diseases that start with R, S, T, C W, Y
Rabies
Rubella
Severe Acute Respiratory Syndrome (SARS)
Scarlet fever
Smallpox
Tetanus
Tuberculosis
Typhus
Viral haemorrhagic fever (VHF)
Whooping cough
Yellow fever
A pt chart shows hypokalemia which antihypertensice medication would you avoid?
a) Irbesartan
b) Lisinopril
c) Ramipril
d) Spironolactone
e) Furosemide
THE ANSWER IS E
A-D causes HYPERkalemia which is ‘fine’
However, diuretics (loop and thiazide) cause hypokalemia so you wouldn’t want to add Furosemide
What malarial prophylaxis is suitable in epilepsy
Atovaquone with proguanil
or
Doxycycline
What malarial prophylaxis is suitable in pregnancy
Chloroquine and Proguanil (+folic acid)
consider Mefloquine in 2nd-3rd trimester
Antimalarial in someone taking warfarin rule
start 2-3 weeks before depatrure
INR must be stable. Measure 7 days before starting prophylaxis and after completing the course
Nish is taking Aripiprazole 15mg OD. what is the least suitable antimalarial?
a) Chloroquine
b) Chloroquine with Proguanil
c) Mefloquine
d) Proguanil
e) Atovaquone with Proguanil
THE ANSWER IS C
Mefloquine is contra-indicated in individuals with a history of psychiatric disorders (including depression) or conclusions
Aripiprazole is used in Schizophrenia and Mania
What to do if taking warfarin and experience a major bleed
Stop warfarin
give Phytomenadione (Vit K1) by slow IV
give dried prothrombin complex (fresh frozen if unavailable)
What to do if taking warfarin. INR >8.0 and minor bleed
Stop warfarin
give Phytomenadione (Vit K1) by slow IV
repeat vit K1 if INR is still high after 24hrs
restart warfarin when INR <5.0
What to do if on warfarin. INR >8.0 and no bleed
Stop warfarin
give Phytomenadione (Vit K1) ORALLY using IV preparation
repeat vit K1 if INR is still high after 24hrs
restart warfarin when INR <5.0
What to do if INR 5-8 with minor bleeding
Stop warfarin
give Phytomenadione (Vit K1) by slow IV
resart warfarin when INR <5.0
What to do if INR is 5-8 with no bleeding
withhold 1 or 2 doses and reduce maintenance dose
what to do if taking warfarin and there is unexpected bleeding at therapeutic levels
investigate the underlying cause
What level of renal function is an eGFR <15
Kidney failure
What level of renal function is an eGFR 15-29
Severe reduction
What level of renal function is an eGFR 30-44
Moderate - severe reduction
What level of renal function is an eGFR 45-49
Milde - moderate reduction
What level of renal function is an eGFR 60-89
Mild reduction… relative to normal range for a young adult
What level of renal function is an eGFR >90
Normal
A few months later, Mrs Aslam collects a prescription for Amiodarone, citalopram and atenolol tablets, and buys grapefruit juice. You contact her doctor to discuss possible interactions. Which of the following is false?
a) Citalopram and amiodarone can both prolong the QT interval
b) Amiodarone and atenolol can both cause bradycardia
c) Grapefruit juice increases exposure to amiodarone
d) Atenolol and amiodarone taken together increase the risk of cardiovascular
side effects
e) Amiodarone and citalopram can both cause hyponatraemia
The answer is E
Citalopram causes Hyponatraemia
Amiodarone affect Potassium
Mr Winks then tells you the medication he is currently taking. You suggest to Mr Winks that it may be one of his medicines causing his dry eyes and mouth. Which of the following medications is most likely to be causing his dry mouth?
a) Amlodipine
b) Olmesartan medoxomil
c) Oxybutynin
d) Piroxicam
e) Salbutamol
The answer is C as its an antimuscarinic
a) Amlodipine - CCB
b) Olmesartan medoxomil - ARB
c) Oxybutynin - ANTIMUSCARINIC
d) Piroxicam -NSAID
e) Salbutamol - B2 AGONIST
What reverses Digoxin toxicity
Digoxin-specific antibody fragments
A junior doctor wants to administer diazepam to one of his patients who is suffering from convulsive status epilepticus. However, there are not any intravenous injections available on the ward so she asks you for an alternative.
Based on your knowledge of drug absorption and the available formulations, which one of the following would you recommend to the junior doctor?
a) Diazepam buccal tablet
b) Diazepam patches
c) Diazepam intramuscular injection
d) Diazepam oral solution
e) Diazepam enema
The answer is E, enema
Cabergoline what is it? Other drugs in same class? and key side effects
is a stimulant of dopamine receptors (agonists) in the brain and inhibits the pituitary’s release of prolactin.
Other drugs in this call are
Amantadine hydrochloride; Apomorphine hydrochloride; Bromocriptine; Pramipexole; Quinagolide; Ropinirole; Rotigotine
Main side effects include
- IMPULSE CONTROL DISORDERS e.g gambling, hypersexuality, binge eating
- Monitored for dyspnoea, persistent cough, chest pain, cardiac failure, and abdominal pain or tenderness