Mock 3 Flashcards
What is the diagnostic first line investigation for heart failure?
Raised NT-proBNP on blood work
What is the gold standard investigation in heart failure?
Echocardiogram
What is ejection systolic murmur indicative of?
Aortic stenosis
What is pan systolic murmur indicative of?
Mitral regurgitation
What are the 5 CXR signs of heart failure?
ABCDE! Alveolar oedema Kerley B lines (interstitial oedema) Cardiomegaly Dilated upper lobe vessels Pleural effusion
What is sawtooth flutter waves seen in?
Atrial flutter
What ECG abnormality is characteristic of Wolf-Parkinson-White syndrome?
Delta waves
What ECG abnormality is seen in acute pericarditis?
Saddle shaped ST segment elevation
A 19-year-old male suddenly collapses whilst playing a football match for his local team. Paramedics arrive rapidly and find him in cardiac arrest and attempt to defibrillate him. His brother who was playing football with him tells you that he’s normally fit and well but for the past few months he had been experiencing some chest pain, palpitations and unexplained syncope. His brother also mentions that their dad died at a young age due to “some heart problems”. What is the most likely cause of this patient’s cardiac arrest?
A. Atrial fibrillation.
B. Aortic stenosis.
C. ST elevation myocardial infarction (STEMI).
D. Non-ST elevation myocardial infarction (NSTEMI).
E. Hypertrophic cardiomyopathy.
Hypertrophic cardiomyopathy
Give 3 types of cardiomyopathy
- Dilated
- Hypertrophic
- Restrictive
What are U waves seen in?
Hypokalaemia
What are 4 ECG abnormalities seen in hyperkalaemia?
- Absent P waves
- Long PR interval
- Wide QRS complex
- Tall tented T waves
(Go, go long, go wide, go tall = gonner)
What is the treatment goal in hypertension?
140/90
Are patients warm or cold in septic shock?
Warm
Describe heart rate in septic shock
Tachycardic
Describe heart rate in cardiogenic shock
Bradycardic
What kind of shock is a bounding pulse seen in?
Septic shock
What kind of pain is aortic dissection described as?
Tearing/shearing that goes to the back - also characteristic of AAA (MEDICAL EMERGENCY)
What kind of chest pain is seen in acute pericarditis?
Sharp, pleuritic chest pain that is worse on lying down and better when leaning forwards
An 84-year old gentleman is rushed into A&E with sudden onset epigastric pain which radiates to the back. Vital signs: HR: 112, BP: 92/63, RR: 36, O2: 89%, Temperature: 37C. His hands are cold and clammy. What investigation is it important to do first? A. Chest Xray B. Coagulation screen C. MRI D. TroponinI E. Ultrasound scan
Ultrasound scan
His vital signs suggest shock and an USS of an aorta would be used to exclude an AAA that would need immediate surgery
What are the typical symptoms of Graves’ ophthalmology?
Diplopia and eye pain
What is the gold standard test for acromegaly?
IGF-1 Test
What does IGF-1 do?
Stimulate skeletal and soft tissue growth
What is the number one cause of secondary hypoadrenalism?
Long term corticosteroid use
What test is diagnostic for Addison’s disease?
Synacthen Test - an infusion of ACTH
Describe the electrolyte imbalance seen in SIADH
Hyponatremia
What are carcinoid tumours?
Tumours of enterochromaffin cells
What is the immediate management for a patient with suspected carcinoid syndrome?
Somatostatin analogue
Give 3 symptoms of hypocalcaemia
Paraesthesia of extremities
Wrist flexion on BP cuff inflation
Facial twitching when tapping facial nerve
What is faecal calprotectin used to differentiate between?
IBS (normal) and IBD (raised)
What is angular stomatitis?
Soreness at corners of lips
Give 4 symptoms of coeliac disease
Weight loss
Steatorrhea
Mouth ulcers
Angular stomatitis
What is the most common cause of small bowel obstruction?
Surgical adhesions
What is the most common cause of large bowel obstruction?
Malignant tumours
What would an enlarged Virchow’s (left supraclavicular) node suggest?
Gastric cancer
Give an example of a drug used to treat Mild UC
Mesalazine
What is used to treat severe UC?
IV Hydrocortisone
What kind of anaemia does chronic disease cause?
Normocytic/microcytic
What disease is auer rods seen in?
AML
Describe the WCC in AML/ALL
Raised
What are bite cells characteristic of?
G6PD Deficiency
What does MGUS predispose a pt to develop?
Myeloma
Describe the WCC in Hodgkin’s
Normal
What are bench jones proteins and rouleaux formation seen in?
Myeloma
Give 4 features/complications of Polycthaemia Vera Ruba
Dizziness
Itching
Haemorrhage
Thrombosis
What is PCV?
A condition where the bone marrow overproduces blood cells - usually due to a JAK2 mutation
Where is kussmaul breathing seen?
DKA
It is deep laboured breathing - a form of hyperventilation to get rid of CO2 in the blood
What is asterixis?
A jerking movement of the hand that occurs when the arms are outstretched and wrists extended (cocked back towards the face), it is more commonly known as liver flap and can be seen in liver or type 2 respiratory failure.
What is painless jaundice characteristic with stool and urine abnormality of?
Cancer of the pancreatic head
What kind of cancer does benzene exposure have a risk of?
Renal cell carcinoma
What is the mode of inheritance for alpha-1 antitrypsin deficiency?
Autosomal recessive
What disease is associated with rice water stools?
Cholera
What is the best treatment for patients with profuse diarrhoea?
Rehydration with IV Fluids
What does campylobacter jejune cause ?
Bloody diarrhoea
What presents with jaundice, fatigue, joint pain, frequency and erectile dysfunction?
Haemochromatosis
What is the gold standard investigation for Wilson’s disease?
Liver biopsy
What is immediately given to patients with suspected meningococcal septicaemia?
Benzylpenicillin
What is the classical triad of presentation of encephalitis?
Fever, altered mental state, headache
What is given in hospital for encephalitis?
Acyclovir
Describe the 5 stages of the MRC dyspnoea scale
Grade 1: Breathless with strenuous exercise.
Grade 2: Short of breath when hurrying or when walking up hill.
Grade 3: Walks slower than people of the same age or stops for breath when walking at own pace on flat.
Grade 4: Stops for breath after walking 100m on flat.
Grade 5: Too breathless to leave the house/ Breathlessness on changing clothes.
What is seen in Wegner’s granulomatosis?
C-ANCA
Describe COPD management pharmacologically
1) SABA / SAMA
2) *If steroid responsive/asthmatic = Add LABA + ICS
2) *If not steroid responsive / non-asthmatic= Add LABA + LAMA
3) Oral theophylline
4) Long term oxygen therapy
What is diagnostic for sarcoidosis?
Tissue biopsy showing non-caseating granuloma
What is a common cause of extradural haemorrhage?
Trauma to the temple causing a tear in the middle meningeal artery
What is seen on CT in extradural haemorrhage?
Lens shaped/ lentiform / bi-convex haematoma
What are the symptoms of a migraine?
POUND Pulsating Onset 4-72 hrs Unilateral Neurological signs (photophobia) Disabling
Describe how a subarachnoid haemorrhage presents
THUNDERCLAP HEADACHE
Meningism
Severe
Occipital
What is the most common cause of a subarachnoid haemorrhage?
Berry aneurysm rupture due to PKD
How would you investigate for SAH?
CT head that would be normal, then lumbar puncture AFTER 12 HOURS looking for xanthochromia
Who is at risk of a subdural haemorrhage?
Elderly
Alcoholics
Those on anti-coagulation or anti-platelets
What would be seen on CT in subdural haemorrhage?
Sickle-shaped / crescent shaped haemotoma
What is a jacksonian motor seizure/ Jacksonian march?
A feature of frontal lobe seizure with proximal spread of clonic jerking spreading from finger/toe/corner of mouth
What kind of seizure does this symptom set describe?
Jacksonian march
Post-ictal Todd’s paralysis/weakness
Head/leg movements
Frontal lobe
What kind of seizure does this symptom set describe?
Floaters/flashes in eyes
Occipital lobe
What kind of seizure does this symptom set describe?
Paraesthesia and non specific sensory symptoms
Parietal lobe
What kind of seizure does this symptom set describe?
Pre-seizure - aura (hallucinations, epigastric rising, emotional)
Seizure - automatisms e.g. chewing and picking at clothes
Post-ictal confusion
Temporal lobe
Stroke of what artery caused “Locked in” syndrome?
Basilar artery
In anterior circulation stroke, which side is affected?
THE OPPOSITE SIDE
Describe the symptoms of left anterior cerebral artery stroke
Right sided hemiparesis/sensory loss
Usually lower limbs
Describe the symptoms of a left MCA stroke
Right sided weakness/sensory loss Usually affects upper limbs Facial weakness with forehead sparing Right sided homonymous hemianopia Dysphasia due to dominant side affected
Why is dysphasia not seen in right MCA stroke?
The left lobe is dominant
What is Brown-Sequard syndrome?
Lateral hemisection of the spinal cord
What are the features of Brown-Sequard syndrome?
Ipsilateral weakness and loss of proprioception and vibration
Contralateral loss of pain and temperature