MOA Flashcards

1
Q

Benzodiazepines

A

Bind to receptor sites on Y-amino butyric acid(GABA)

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2
Q

SSRI

A

Blocks reuptake of serotonin

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3
Q

SNRI

A

Blocks re-take of serotonin and norepinephrine

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4
Q

TCAs

A

Blocks reuptake of norepinephrine OR serotonin

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5
Q

MAOIs

A

Prevent enzymes from breaking down catacholamines

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6
Q

Bipolar agents

A

Unknown

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7
Q

Antipsychotics

A

Blocks dopamine receptors in dopamine pathways

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8
Q

Sedatives

A

Interact with gaba-benzodiazepine receptor complexes

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9
Q

ADHD

A

Stimulates CND activity; blocks re-take and increases release of norepinephrine and dopamine in neuronal space

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10
Q

Hydantoins

A

Binding to voltage dependant sodium channels

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11
Q

Valproates

A

Enhanced inhibitory actions of gaba

Divalproex
Valproic acid

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12
Q

Iministilbenes

A

Unknown

Carbamazepine

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13
Q

Y aminobutryric acid analogs

A

Increases GABA turnover without binding to the GABA receptor

Gabapentin
Prevailing
Tiagabine

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14
Q

Other seizure meds

A

Inhibits voltage dependant sodium channels

Lamotrigine
Levetiracetam
Topiramate
Zonisamide

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15
Q

Barbiturates for seizures

A

Enhances GABA receptors by binding GABA receptors to barbiturate receptors

Phenobarbital
Primidone

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16
Q

Parkinsons- amantidine

A

Stimulates release of dopamine from neuronal stores

17
Q

Parkinsons-Benztropine

A

Anticholinergic-blocks action of acetylcholine

18
Q

Parkinsons-Bromocriptine, pramipexole, ropinirole

A

Dopamine agonist

19
Q

Parkinsons- levodopa/carbidopa

A

Synthesis if dopamine inside the brain and blocks conversion outside the brain

20
Q

Parkinsons- levidopa/carbidopa/entacapone

A

Synthesis of dopamine inside the brain plus COMT conversion

21
Q

Parkinsons- rasagiline, selegiline

A

Blocks degradation of dopamine by inhibiting MAOI