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PTCB > Chapter 1 #2 > Flashcards

Chapter 1 #2 Flashcards

1
Q

Antiprotozoals MOA

A

Stops multiplication of microorganisms and arrests the disease

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2
Q

Antiprotozoals drug interactions

A

Beta blockers and CCB

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3
Q

Antiprotozoal examples

A 
Chloroquine
Mefloquine
Metronidazole 
Praziquantel
Primaquine

All tablets

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4
Q

Selective estrogen receptor modulators MOA

Antineoplastic agents

A

Inhibits synthesis of adrenal steroids

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5
Q

Selective estrogen receptor modulators drug interactions

Antineoplastic agent

A

Eliglustat, fibanserin, lomitapide

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6
Q

Selective estrogen receptor modulators examples

Antineoplastic agent

A

Tamoxifen
Toremifene

Tablets

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7
Q

Estrogen receptor downregulators MOA

Antineoplastic agent

A

Inhibits estrogen activity by causing changes in estrogen receptor function and triggers estrogen receptor degradation

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8
Q

SERM and Estrogen down regulate indication

A

Breast cancer

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9
Q

Aromatase Inhibitor MOA

Antineoplastic

A

Blocks production of aromatase by adrenal gland

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10
Q

Aromatase inhibitors drug interactions

A

DHEA, estradiol, and tamoxifen

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11
Q

Aromatase Inhibitor examples

A

Anastrazole
Exemestane
Letrozole

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12
Q

Aromatase Inhibitor caution

A

Take same time everyday w water and meals

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13
Q

Gonadotropin-releasing hormones agonists MOA

Antineoplastic agent

A

Increases hormone levels and is followed by desensitization to hormones effect

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14
Q

Gonadotropin-releasing hormones agonists drug interactions

A

Cisapride, dronedarone, pumozide

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15
Q

Gonadotropin-releasing hormone agonists example

Antineoplastic

A

gosereline (Zolvadex)

Implant

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16
Q

Progestins MOA

Antineoplastic

A

Suppresses release of luteinizing hormone from pituitary glands and increases metabolism of estrogen

17
Q

Progestins drug interactions

Antineoplastic

A

Dofeilide and oral hypoglycemic

18
Q

Progestins examples

A

Megestrol tabs and suspension

19
Q

Alkalating agent MOA

Antineoplastic

A

Forms irreversible cross-links on DNA, resulting in cells being unable to reproduce

20
Q

Alkylating agents drug interactions

Antineoplastic

A

Antigout meds and vaccines

21
Q

Alkylating agent indication

Antineoplastic

A

Hodgkin lymphoma

22
Q

Alkylating agents example

Antineoplastic

A

Cyclophosphamide-tab, powder for inj

Estramustine- capsule

PTCB (3 decks)

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