mmb vm Flashcards

1
Q

What can investigators do and what can’t they do in an observational study?

A

Do: Investigator may make inquiry, observe, measure different factors and record what happes to study participants
Can’t: Cannot intervene

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2
Q

What can investigators do i an intervention study?

A

Intervene in a pre-planned way and then measures or records the outcome

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3
Q

What are the types of observational studies ?

A

Ecological
Cross-sectional
Case-control
Cohort

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4
Q

What are the types of intervention/ experimental studies?

A

Non-randomised intervention study
Randomised controlled trial (RCT)

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5
Q

What is a cohort study?

A

A cohort is a defined group of people who are followed up prospectively

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6
Q

What does an observational study examine?

A

Examine link between an exposure and disease outcome

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7
Q

What can an exposure be ?

A

Risk and protective factor

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8
Q

What is an example of an observational study?

A

Does daily aspirin reduce risk of alzheimer’s?

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9
Q

What are the types of exposures?

A

Host
Environment
Agent/disease

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10
Q

What is a cross-sectioal study?

A

An observational design that surveys exposure and disease status at a single point in time (a cross-section of the population) (exposure and disease measured at once

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11
Q

What type of study is a cohort study?

A

Typically prospective

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12
Q

What is a cross-sectional study?

A

Measure exposures and disease status at one point in time

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13
Q

What is a cohort study?

A

Identify groups by exposure and look forward to disease outcome

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14
Q

What is a case-control study?

A

Identify groups by disease status and look backwards to exposure

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15
Q

How do you designa cohort study?

A

1.Group of people without the disease
2.Divided into a group who are exposed to the factor and group who are not exposed to the factor
3.Than measure who if each group has developed and who hasn’t developed the disease

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16
Q

What are the features of a cohort study?

A

1.Prospective or longitudinal study
2.Subjects classified by exposure status and followed up over a period of tme to determine disease outcome
3.Usually need a large population even if the disease is common
4.Typically study cause of disease
5.Usually examine many hypotheses and often examine several different disease ouutcome

17
Q

What makes cohort studies special?

A