Mixed Flashcards
A 65-year-old man presents with a history of pain in the calf for the last two years. In last six months he was able to walk 300 yards and now is only able to achieve 50 yards. He rests for five minutes between periods of walking.
Intermittent claudication
Atherosclerosis affects the entire circulation. Disease in one anatomical region suggests that other regions are also diseased and therefore if a patient has carotid stenosis he may well have intermittent claudication, angina pectoris and an aortic aneurysm.
When taking a history and performing an examination of patients, all vascular regions should be examined. Symptomatic stenosis of greater than 70% in the carotids requires operative intervention with a carotid endarterectomy.
Patients with abdominal aortic aneurysms greater than 5-5.5 cm require inlay grafting, and patients with critical ischaemia in their limbs or rapidly deteriorating claudication distance require angioplasty or bypass surgery.
Clearly patients should be assessed for their fitness for surgery, since many have multiple co-existing diseases.
A 56-year-old diabetic attends his GP complaining of an ulcer on the heel of his foot. He has had diabetes for 20 years and is known to be poorly compliant with his medication. The GP examines his lower limb and elicits a reduction in sensation to vibration and light touch.
Neuropathic ulcer
A 76-year-old man presents to the hospital with an episode of amaurosis fugax. The physician finds a bruit in the left carotid artery and he is sent for duplex colour flow Doppler imaging.
Carotid stenosis
A 66-year-old man has undergone an anterior resection of the rectum and is making a slow recovery. He complains that in the middle of the night he has pain in the left calf. On examination he has a tender left calf which is slightly swollen and red. He has been given subcutaneous heparin throughout his hospital stay.
Deep venous thrombosis
A 22-year-old man presents to the Emergency department following an accident at work. A piece of scaffolding fell from two metres above him and trapped his left leg. His peripheral pulses are present on arrival in hospital two hours after the accident. He is admitted for observation when he becomes hypotensive with a poor urine output.
Rhabdomyolysis
A 64-year-old man with a tumour of the upper femur.
Hindquarter amputation
A 85-year-old man with pain and deformity of the left knee due to congenital malformation. He was able to walk up until the last five years when the pain became unbearable.
Above knee amputation
A gangrenous toe due to peripheral vascular disease with superimposed infection in a 70-year-old diabetic.
Ray amputation with “racket incision”
Ischaemic gangrene of the lower leg with ulceration over the medial malleolus and spreading infection proximally.
Below knee amputation
A 90-year-old lady who is immobile due to severe osteoarthritis in the hips and knees. She has developed marked arterial ulceration in the right lower limb. She is requires full nursing care.
Above knee amputation
The indications for amputation are ischaemia, tumours, pain and deformity. 80-90% of amputations are performed for ischaemic gangrene secondary to peripheral vascular disease.
Diabetics have large and small vessel disease and a ray amputation of the toes is often the first stage of a series of amputation levels. Where pain and deformity cannot be alleviated by medical means, amputation is the final option.
Supracondylar amputations have the advantage of a longer stump which allows the patient to turn in bed, however the stump is usually not long enough to fit an internal knee mechanism prosthesis and thus is unpopular. Where the patient is already immobile, it is may be a practical option.
Performed where other investigations have failed to identify whether a lump is malignant or benign.
Excision biopsy
Can be used in symptomatic and asymptomatic patients. It is 80-95% accurate and part of the United Kingdom screening programme.
Mammography
Usefully identifies cysts and is able to study abnormal tumour circulation.
Ultrasound
Used in the histological diagnosis of impalpable lesions which are suspicious of malignancy. Requires a general anaesthetic.
Wire-guided biopsy
Very helpful in establishing the presence and extent of metastatic disease.
Bone scan
The management of a patient with breast cancer requires the achievement of a diagnosis and staging of the disease.
Examination identifies palpable characteristics
Ultrasound reveals if the lump is solid or cystic, thin or thick
Mammography identifies changes in architecture and calcification and
Spiculation, cytology or histological examination confirms the presence of malignancy, the type, and hormone receptor status.
Metastatic spread can be identified by CT, MRI and bone scans.
A premenopausal 42-year-old lady experiences marked premenstrual breast nodularity and discomfort of the upper outer quadrant. Fine needle aspiration cytology is performed and no malignancy is found. A core-biopsy reveals multiple cysts, fibrosis and epitheliosis.
Benign mammary dysplasia
In this case the biopsy with multiple cysts, fibrosis and epitheliosis is characteristic of benign mammary dysplasia.
A 45-year-old lady, premenopausal, with a discrete smooth breast lump presents to her GP. Aspiration is attempted and reveals a yellow/brown/green fluid. There is absence of blood staining. The GP refers her to a breast clinic where she has a mammogram and ultrasound. The lump is no longer present.
Cystic disease
This woman is likely to have cystic breast disease.
A 26-year-old lady presents with a hot, red, swollen lump in her left breast which is very tender. She is one month post partum of her first child.
Lactational breast abscess
The 26-year-old post partum woman has typical features of a breast abscess and this is likely to be lactational.
A 50-year-old lady describes an intermittent discharge of clear, cheese-like fluid with occasional blood staining. Her nipple has become retracted. Fine needle aspiration (FNA) cytology has been performed and reveals benign cells. Some coarse calcification is seen on her mammogram.
Duct ectasia
The FNA of the 50-year-old woman shows benign breast disease, but the calcification on mammography suggests duct ectasia.