MIX 1 QBANK

Question 1

vitamin K dependent factors

Answer 1

2, 7, 9, 10
Protein C
Protein S.

Gamma carboxylatIion of glutamate residues

Question 2

malignancy rates for pancreatic neuroendocrine tumors

Answer 2

insulinoma 10% - In the most common evenly distributed and pancreas
VIPoma 50%
Gastrinoma 70%
Somatostatinoma 90%
Glucagonoma 90%

Question 3

mechanism of cyclosporine

Answer 3

findings to cytoplasmic protein cyclophilin (“cyclosporine”)
inhibitor tyrosine phosphate calcineurin (“C” is for cyclosporine)
prevents transcription of IL 2 gene

Question 4

substrate for gluconeogenesis

Answer 4

glycerol
Lactate
pyruvate

the medial acid (except leucine and lysine)

Question 5

With MEN 2A and 2B what percent have pheochromocytomas

Answer 5

40-50%

Question 6

common initial presentation of MEN 1

Answer 6

hypercalcemia from hyperparathyroidism

Question 7

by what age should MEN 2A patient’s have thyroidectomy

Answer 7

5?

Question 8

list prognosis of medullary thyroid carcinoma regarding MEN syndromes, familial medullary thyroid carcinoma, sporadic

Answer 8

MEN 2A and familial have better prognosis than MEN 2B or sporadic