Mitosis and meosis Flashcards
What is the chromosome structure
Identical chromatids held together by a centromere.
Short top arm = P.
Long bottom arm = Q.
Telomeres found at the end
Metacentric, submetacentric, acrocentric and telocentric mean what?
Different potsitions of centromere. Centromere gets higher in respective order, P arm becomes shorter.
Describe mitosis
Division of somatic cells
1) Propahase - nuclear membrane disintegrates and protein called kinetichore binds to centromere
2) prometaphase - kinetichore attaches to spindle fibres
3) metaphase- chromosomes line up on metaphase plate
4) kinetichore fibres attached to spindle and centromere shorten pulling chromatids to opposite poles
5) telophase- nuclear envelope reforms and cytokensis beings
What are homologous chromosomes?
2 same chromosomes but one maternal and one paternal
Describe meiosis
Division of germline cells
Describe meiosis
Division of germ line cells= four non-identical cells. 2n->n
Meiosis 1
Homologous chromosomes line up and separate
Meiosis 2
Chromosomes line up and chromatids separate
Random assortment of chromosomes and crossing over leads to variation
What is spermatogenesis?
Cell division to produce male gametes
Spermatogonium (2n) is the germ line stem cell. Differentiates into primary spermatocyte which divides by meiosis to produce 4 spermatids (60 day process).
What is oogenesis?
Oogonium (2n) differentiates into a primary oocyte (2n) which divides my meiosis to produce 4 cells. 1 of these is the mature ovum and 3 of these are the polar bodies. Mature ovum is larger because takes all of cytoplasm. Polar bodies are disregarded. (12-50 years)