Mitosis and Meiosis Part 2 Flashcards

1
Q

Where is Meiosis seen

A

Meiosis is a special type of cell division for germline cells. (The cells that form eggs in females and sperm in males.)

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2
Q

What does Meiosis Produce

A

Meiosis produces four non-identical cells with half the chromosome complement of the parental cell

One round of replication is followed by TWO rounds of cell division (meiosis I and meiosis II)

A diploid (2n) cell becomes haploid (n)

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3
Q
A
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4
Q

How long can prophase last in mammals

A

Prophase can last up to several days in mammals! Recombination takes time

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5
Q

What are the stages of Meiosis 1

A

Prophase. 1
Metaphase. 1
Anaphase. 1
Telophase. 1

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6
Q

What happens in prophase 1

A

Nuclear membrane reforms

Chromosome decondense

Cytokinesis occurs

During prophase I homologous chromosomes pair
up (bivalents)

Crossing over occurs (chiasmata)

Recombinant chromosomes are formed

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7
Q

What happens is recombination

A

In bivalent forms, crossing over occurs, this produces genetically different daughter chromosomes,
(switch in alleles)

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8
Q

What happens in Metaphase 1

A

Spindle forms and chromosomes line up at centre of cell at the Metaphase Plate

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9
Q

What happens in anaphase 1

A

Kenesin motors move two halves of the chromosomes to each side of the cell
(Chromosomes migrate to either side of cell)

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10
Q

What happens in Telophase 1

A

Nuclear membrane reforms

Chromosome decondense

Cytokinesis occurs

A cleavage furrow forms turns cells in to two daughter cells

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11
Q

What happens in Meiosis II

A

Prophase. 2
Metaphase. 2
Anaphase. 2
Telophase. 2

In meiosis II the same steps take place but without DNA
replication

Chromosomes separate to form chromatids

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12
Q

What number of chromosome are produced from Meiosis II

A

cells that are produced have half the number
of chromosomes - haploid

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13
Q

What are the stages of prophase I
what are they

A

Leptotene,- Chromosomes condense
Zygotene, - Synapsis between different homologous chromosomes (where they bind to eachother)
Pachytene, - Crossing over
Diplotene, - Dissolution of Synaptonemal Complex
Diakinesis. - Dissolution of nuclear Membrane once recombination has occurred

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14
Q

What is the consequences of Meiosis

A

Maintaining constant number of chromosomes from generation to generation -
Generation of genetic diversity:
1.Random assortment of chromosomes
2.Crossing over of genetic material

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15
Q

Meiosis in males - spermatogenesis
what is this

A

1 spermatocyte (2n) gives rise to 4 sperm (n)

Length of spermatogenesis is ~60 days

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16
Q

Meiosis in females - oogenesis
What is this

A

1 oocyte (2n) gives to rise to 1 egg (n) + 3 polar bodies ( these aren’t used in reproduction)

Length of oogenesis is 12-50 years!

17
Q

What is caused by Non-Disjunction during Meiosis

A

Aneuploidy is the condition of having an abnormal number of chromosomes in a haploid organism

Aneuploidy can be caused by non-disjunction during mitosis or meiosis.

A failure to separate pairs of chromosomes lined up at the metaphase plate can produce daughter cells with abnormal chromosome numbers

(1 chromosome instead of 2) - Mosaicism
(3 chromosomes instead of 1) - Trisomy

18
Q

What is Non-Disjunction

A

Unequal distribution of chromosomes caused by failure to segregate properly during meiosis

19
Q

Difference between gene and allele

A

an allele is a variant form of a gene.