Mitosis And cell Division Flashcards
1
Q
What are cyclins?
A
Key proteins for cell cycle
Activates CDKs that phosphorylase distinct sets of proteins necessary for progession of the cell cycle phases.
Levels of cyclin is controlled by transcription and degradation
2
Q
What is APC/C?
A
Ubiquitin ligase that marks protein for degradation
3
Q
Functions of cohesin?
A
Keeps sister chromatids connected during mitosis
Involved in spindle attachment onto chromosomes
Facilitates DNA repair
4
Q
What are the four phases ?
A
G1 - growth or gap phase 1
S - synthesis phase - DNA replication
g2 - growth or gap 2
M - mitosis and cytokinesis - division
