Mitosis and Cancer

Question 1

At the cell level, what is cancer?

Answer 1

Uncontrolled cell growth that have DNA replication errors

Question 2

What are proto-oncogenes?

Answer 2

Genes that code for positive cell cycle regulators.

Question 3

How do oncogenes cause a cell to become cancerous?

Answer 3

Can cause cell checkpoint to be activated before the necessary conditions to move forward with division are met

Question 4

When does a Proto-oncogene become an oncogene?

Answer 4

When the Proto-oncogene has been altered such that there is an increase in the cell cycle

Question 5

What do negative regulator proteins do?

Answer 5

Prevent cell cycle from continuing if certain factors are not met

Question 6

What are the most well known tumor suppressor genes called?

Answer 6

Retinoblastoma protein, p53, and p21

Question 7

What is apoptosis and why might it be triggered?

Answer 7

Programmed cell death. Triggered in cells if abnormalities or DNA damage cannot be repaired.