Mitosis Flashcards
Metabolic Awakening
Egg cytoplasmic pH rises 6.8->7.2 (triggers increase in protein synthesis)
Changes in cytoskeleton microtubules rearrange to allow pronuclear migration
Preparation for Cleavage
Sperm delivers nucleus & MTOC (centriole)
Karyotype
The array of all chromosomes in a cell
Chromosomes
String like. 40% DNA+60% Proteins = Chromatin Thread like (1st), condensed (2nd)
Mitosis
Process where duplicated chromosomes divide & daughter chromosomes separate w/ 2 genetically identical nuclei
Centromere
Chromosomes are attached here
Kinetochore
Protein disk that is attachment sight for MTs
Prophase
Replicated chromosomes become condensed –> spindle forms by MT growth from replicated centriole
Prometaphase
Nuclear envelope breaks down, MTs from spindles bind to kinetochores
Metaphase
MTs have aligned chromosomes on midline of spindle
Anaphase
Centromere region divides freeing the sister chromatids from each other
MTs connecting centriole to kinetochore shortens –> separating the sister chromatids
Telophase
- nuclear envelopes reform
- spindle disassociates
- chromosomes de-condense
Cytokinesis
Division of cytoplasm into 2 daughter cells
Morphogens
- molecules in cells that trigger specific activity
- bind to chromosomes for new proteins to turn on/off genes
Hyaline layer
Holds the cell together at the 2-cell stage