Mitosis Flashcards
what is mitosis?
nuclear division
when is mitosis necessary?
when all the daughter cells have to be identical.
- growth
- replacement
- repair
- asexual reproduction
what is asexual reproduction?
the production of genetically identical offspring from one parent in multicellular organisms.
how do prokaryotic organisms divide?
binary fission
what is each chromosome converted into before mitosis?
two identical DNA molecules called chromatids.
what joins the two chromatids together?
a centromere
why is it necessary to keep chromatids together?
so they can be precisely manoevred and segregated equally, one each into the two new daughter cells.
how is chromatin formed?
DNA combines with proteins called histones to form a dense complex called chromatin.
what are the stages of mitosis?
- prophase
- metaphase
- anaphase
- telophase.
what happens during prophase?
- chromatin fibres begin to coil and condense to form chromosomes
- the nucleolus disappears
- nuclear membrane begins to break down.
- protein microtubules form spindle-shaped structures linking the poles of the cell.
- centrioles migrate to the opposite poles of the cell.
- spindle fibres attach to specific areas on the centromeres and start to move the chromosomes to the centre of the cell
- by the end the nuclear envelope has disappeared.
what happens during metaphase?
- chromosomes are moved by spindle fibres to form a plane in centre of the cell (metaphase plate) and then held in position.
what happens during anaphase?
- centromeres holding pairs of chromatids divide.
- chromatids are seperated (pulled to opposite poles of the cell by shortening spindle fibres.)
- characteristic v shape formed as chromatids are dragged by their centromeres through the liquid cytosol.
what happens during telophase?
- chromatids have reached the poles and are now called chromosomes.
- two new sets of chromsomes assemble at each pole and the nuclear envelope reforms around them.
- the chromosomes start to uncoil
- nucleolus reformed
- cytokinesis begins.
how does cytokinesis occur in animal cells?
- a cleavage furrow forms around the middle of the cell.
- cell surface membrane is pulled inwards by the cytoskeleton until is it close enough to be fused around the middle, forming two cells.
why cant plants form a cleavage furrow?
plant cells have a cell wall so it is not possible.