Mitochondria Flashcards
what are two examples of important cofactors in mitochondria
Flavins and quinone
how do iron-sulpher clusters form
iron atoms liganded by sulpher in the cystine residues of the side chains
what can happen to the iron in the iron-sulpher complex
in can undergo reduction or oxidation
three types of redox carrier
flavins, quinones and iron-sulpher clusters
what does quinone link?
complex 3 to complex 2 and 1
what is complex II referred to as?
succinate dehydrogenase
what is complex III referred to as?
Q cytochrome C oxidoreductase
in what ways can cytochrome be attatched?
via covalent bonds or non-covalent. Type of attachment and environment influences the redox potential
what two routes do the electrons bound to QH2 take?
- transferred via the Riekse FeS centre
2. via two b cytochromes to a second oxidised Q molecule
what is the complex IV
cytochrome C oxidase
what is the mechanism of movement through complex III known as
proton motive Q cycle
what type of cytochrome does complex 4 contain
A type
what type of cytochome does complex 3 contain
B type
what is the F1 subunit of ATP synthase formed of
3 alpha and 3 beta subunits
what of alpha and beta is the catalytic and regulatory subunits?
alpha is the regulatory and beta is the cataylitic
what drives conformational change of alpha and beta
rotation of Fo causing rotation of y
