Missed Chapter 15 Achieve

Question 1

sickle cell anemia

Answer 1

change in amino acid from glutamic acid to valine results in impaired ability for red blood cells to carry oxygen

Question 2

hot spots

Answer 2

where cytosine becomes 5-methylcytosine

Question 3

expanded triplet repeats

Answer 3

CGG repeats
becomes worse in successive generations

Question 4

allele specific nucleotide hybridization

Answer 4

assumes that probes will complementary bind to DNA sequences

Question 5

single nucleotide polymorphisms (SNPs)

Answer 5

nucleotide base pairs at which point mutations have become frequent enough to be identified

Question 6

gene therapy

Answer 6

add a new gene that will be expressed in the appropriate cells
changes the genotype

Question 7

abnormal genes detected via…

Answer 7

DNA

Question 8

loss-of-function mutations

Answer 8

usually recessive

Question 9

UV radiation

Answer 9

causes thymine dimers

Question 10

PKU levels

Answer 10

normal before birth, high after birth if fed normal breast milk

Question 11

gel electrophoresis

Answer 11

• DNA cut with different restriction enzymes is placed in agarose polymer wells in buffer
• current creates + and - ends, DNA travels towards + end
• separates DNA based on size