Miss Duerden's lectures Flashcards
What is the duct of the largest salivary gland?
The Stenson’s Duct
What is geographical tongue?
multiple circular or pink areas on the top of tongue. Sometimes depilation can occur.
What is Linea alba?
A common condition that appears as white slightly raised keratotic line along the occlusal plane of the buccal mucosa.
What is morsicatiobaccarum?
Cheek biting
How can coeliac disease present orally?
Glossitis, angular cheilitis and enamel hyperplasia.
How can Chron’s disease present orally?
swellings of the lips, mucosal tags, oral ulceration and full width gingivitis.
What is ulcerative colitis?
An inflammatory condition which effects the colon.
What is GORD?
Where there is an increased frequency and duration of reflux causing damage to the oesophageal mucosa by regurgitation of the gastric contents.
How does GORD present orally?
Dental erosion
How does hepatic disease effect the patient orally?
Bilirubin in the submucosa affects the mucosa on the soft palate and sublingual region. Excessive gingival bleeding and prolonged bleeding.
What is anaemia?
A reduction in the level of haemoglobin or a decreased number of erythrocytes.
How does anaemia present orally?
Pallor of the oral mucosa, glossitis, oral candidiasis, exacerbation of RAV and plummer vision syndrome.
What is acute leukaemia?
A malignant neoplasm of blood forming tissues characterised by abnormal proliferation of leukocytes originating in bone marrow.
How does acute leukaemia present orally?
Gingival swelling, oral ulceration, leukemic deposits, oral petechiae and purpura.
What are some functions of thrombocytes?
Secrete vasoconstrictors, form temporary platelet plugs, dissolve blood clots, secrete growth factors.
What are purpura?
The typical result of platelet disorders, it is bleeding into the mucous membrane.
What are some causes of platelet diseases?
Idiopathic thrombocytopaenia, connective tissue diseases, leukaemia and HIV infection.
What is the clotting cascade?
Platelets bind to collagen and make a plug, adhesion is strengthened by the vWF it is a temporary measure while the clotting cascade is triggered to make a stronger clot.
What is the intrinsic pathway in the clottingcascade?
The intrinsic pathway is activated by damage directly to the blood vessel and the exposure of collagen to the circulating platelets within the blood.
What is the extrinsic pathway in the clotting cascade?
The extrinsic pathway is activated by many things including damage directly to the blood vessel, tissue damage, tissue damage outside of the blood vessel and inflammation.
What is the common pathway?
Factor 10 is the start of the common pathway. Fibrin traps the platelets and is clotting factor 1. Thrombin activates all the other clotting factors and is clotting factor 2.
What is warfarin?
It is a vitamin K antagonist and blocks vitamin K dependent clotting factors.
What are some non vitamin K oral anticoagulants?
Dabigatran and rivoraxaban.
What is dabigatran?
It is a direct thrombin inhibitor.
What is rivoraxaban?
It is a direct inhibitor of activated factor X.
What are some clinical manifestations of haemophilia A + B?
prolonged bleeding
What is Von Wilbrand’s disease?
A hereditory disease caused by a deficiency of the vWF.
How does von wilbrand’s disease present?
Mucocutaneous bleeding with varying severity.
What is systemic lupus erythematosus?
A multi system autoimmune disease.
How does lupus present orally?
Purpura and ulceration of the buccal mucosa and gingiva.
What is rheumatoid arthritis?
A common multisystem autoimmune inflammatory disease?
Why may a person with rheumatoid arthritis have decreased OH?
Inflammation in the synovial tissue of the joints of the hands and wrists reduce the ability to brush the teeth.
What is Sjogren’s syndrome?
An autoimmune disease affecting fluid secreting glands..
What are the symptoms of Sjogren’s syndrome?
Dry eyes/mouth, parchment-like mucosa and lobulated tongue.
What is scleroderma?
It is progressive fibrosis from increased collagen deposition in interstitium and intima of small arteries and connective tissues.
How is scleroderma relevant to dentistry?
Opening of the mouth becomes restricted, widening of the periodontal ligament and trismus.
What is TB?
It is a bacterial infection, presenting as a typical lesion that is painful and is on the tongue.
What is COPD caused by?
Smoking and recurrent respiratory infections.
How is COPD relevant in dentistry?
It may be linked to periodontal disease and some dental treatments may trigger airway problems.
What is lichen planus?
Bilateral white striations on the buccal mucosa, tongue or gingiva.
What are the types of lichen planus?
Reticular, erosive, atrophic, bullous or plaque like.
What is desquamative gingivitis?
Red, inflamed, smooth gingivae.
What is Erythema Multiforme?
An uncommon acute reaction affecting mucocutaneous tissues seen in young males.
How does oral EM present?
Macules which evolve to blisters and ulcers, lips become swollen.
What is pemphigus vulgaris?
Chronic diseases characterised by epithelial blistering affecting cutaneous and mucosal surfaces.
What are the symptoms of PV?
Blisters that first develop in the mouth and move onto the skin. The blisters can burst and become painful sores.
What is Bullous Pemphigoid?
It is an autoimmune type of disorder with a genetic predisposition characterised by autoantibodies against the connections between epidermal cells.
What is Psoriasis?
A common relapsing skin disease on the lips, tongue palate and buccal mucosa.
What is diabetes?
A common endocrine disease.
How can diabetes manifest orally?
Dry mouth, compromised periodontal health, oral candidiasis and swelling of the salivary glands.
What affect do sex hormones have on gingival health?
Recurrent aphthae, burning tongue, fibrous hyperplasia.
What are the three types of epiludes?
Pregnancy, fibrous and giant cell carcinomas.
How does pregnancy epiludes occur?
It occurs in the mouth as an inflammatory response to plaque.
How can angina present orally?
Angina may present as tooth ache in the lower left quadrant.
What are some ways that HIV can present orally?
Angular cheilitis, oral hairy leucoplakia, varicella zoster and herpes simplex.
What are some bacterial lesions in HIV?
Associated with gingivitis and periodontitis (ANUG)
What is an ulcer?
A breach in the oraal epithelium which typically exposes nerve endings i nthe underlying lamina propria resulting in pain or soreness.
What are the most important features of oral ulceration?
Whether it is single, multiple or persistent.
What may a single persistent ulcer be?
Neoplasia, chronic trauma, chronic skin disease or chronic infection.
What may multiple non persistent ulcers be caused by?
Skin diseases, GI disease, blood disease, drugs or an immune defect.
What are the main causes of ulcers?
Trauma, infections, drug therapy and systemic disease.
What is traumatic ulceration?
Can be physical, chemical or factitious. Usually sensitive to hot, spicy or salty foods. Irregular border with yellow margins. usually heal in 10-14 days.
Detail mechanical trauma.
Often found on the buccal mucosa, caused by ill fitting prosthetics, and biting oneself.
Detail chemical ulcerations.
Can be on any area of the oral mucous membrane. Usually resolve.
Detail thermal ulceration.
Related to hot foods and typically occurs on the posterior buccal mucosa and the palate.
What is recurrent apthous stomatitis?
Outbreaks are sporadic and decrease with age.
What are minor aphthae?
The most common stomatitis, they are small, well defined shallow ulcers with slightly raised erythematous borders.
What are major aphthae?
1cm in diameter, more frequent recurrence, frequently heal with scarring.
What are some associated diseases with aphthous ulcers?
Iron deficiency, GI disturbance, immune disturbances and NSAIDs.
What do you do if you find a persistent ulcer?
Refer for full blood count, serum B12 and folate.
What is Behget’s syndrome?
A rare, chronic and sometimes a life-threatening disorder as a result of inflammation of blood vessels.
What is the clinical diagnosis for Behget’s syndrome?
Any two of the following: -
Recurrent genital ulcers
eye lesions
skin lesions
pathergy
What is the treatment for Beghet’s syndrome?
Needs a multidisciplinary approach. Oral ulcers are treated as aphthae. Thalidomide.
What is herpetiform aphtae?
Multiple pin sized discrete ulcers that occur frequently and heal within 7-10 days.
What do you do to when malignancy is suspected in ulceration?
Patients with a single persisting ulcer for more than three weeks needs a specialist opinion.
What are hyperplastic lesions?
They are a result from chronic irritation, infection, proliferation of granulation tissue and progressive fibrosis.
What is fibroepithelial polyps?
Slow growing, sessile fibrous lumps which are usually firm and painless.
What are histological features of Fibroepithelial polyps?
Non-encapsulated nodular mass of dense, fibrous tissue.
Covered by stratified squamous epithelium - excision required.
What is a peripheral giant cell granuloma?
They are red haemorrhagic and soft. Occasional superficial bone erosion.
What is a Pyogenic granuloma?
Gingival margins have an ulcerated appearance on the top of the ‘lump’. shoudl excise.
What is dental hyperplasia?
Associated with chronic irritation from a denture, should excise.
What is papillary hyperplasia?
Small, multiple nodules from variable inflammation. usually in the palatal vault.
What can jaw swellings be?
unerupted teeth, Tori and multiple exotoses.
What are Tori?
Slow growing and asymptomatic overgrowth of bone. Excise or reduce if there is denture difficulties.
What are multiple Exotoses?
It is the formation of a bone mass on the outer side of the maxilla.
Squamous cells papilloma?
A benign epithelial tumour.
What is n adenoma?
A common benign salivary gland tumour.
What is a fibroma?
Hard or soft and usually broad based. Can be leaf shaped. Very common under dentures and should excise.
What is a neuroma?
Asociated with multiple endocrine neoplasia and may be traumatic.
What is a lipoma?
A benign tumour of adipose tissue, rare, slow growing, painful masses on the the buccal mucosa.
What is a haemangioma?
A developmental lesion of blood vessels, present at birth. Can grow, remain static or regress.
What is a lymphangioma?
A benign tumour of lymphatic channels. It is a rare, colourless lesion but can be purple if bleeding. Must excise.
What is a dental abscess?
Most common cause of oral swelling. Chronic inflammatory and granulomateous disorders can present with lumps or bumps.
What is gingival fibromatosis?
A group of diseases idiopathic or hereditary with generalised fibrous enlargement of the gingivae.
What is Nefidepine?
Calcium channel blocker.
What is pheytoin?
An anticonvulsant