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IHOP > Miscellanous agents > Flashcards

Miscellanous agents Flashcards

1
Q

Bleomycin

A

Inhibits DNA synthesis by creating single and double-strand breaks.

Toxicities:
- Pulmonary Fibrosis
- Idisyncratic Reaction ( bluish/grayish rash)

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2
Q

Procarbazine

A

Alkylating agent- DNA crosslink
MAO inhibtior

Interaction with Thymine

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3
Q

Dacarabazine

A

Alkylating agent- DNA crosslink
— HIGHLY EMETOGENIC—-

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4
Q

Temozolamide

A

Alkylating agent- DNA crosslink
–Lymphopenia–
—- Prophylaxis required—-

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5
Q

Hydroxyurea

A

-Antimetabolite
–Inhibits ribonucleotide diphosphate reductase

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6
Q

Trabectedin

A

Alkylating agent that binds to DNA groove
– Hepatotoxicity–

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7
Q

Mitomycin

A
  • Alkylating agent hat created guanine- cytosine crosslink
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IHOP (5 decks)

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