Antimetabolite Flashcards

1
Q

Glucarpidase (voraxaze)

A

Antitdote for methotrexate toxicity and overdose

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2
Q

Methotrexate

A

Antimetabolite

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3
Q

Premetrexed (Alimta)

A

Anti-folate that inhibits multiple folate pathways

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4
Q

Capecitabine

A

Antimetabolite ( Oral prodrug of 5-FU)

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5
Q

5-FU

A

Antimetabolite

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6
Q

5-FU Infusional MOA

A

TS Inhibiton (Diarrhea, Mucositis, Hand-foot syndrome)

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7
Q

5-FU Bolus MOA

A

RNA false base pair (myelosuppression)

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8
Q

Cytarabine

A

Antimetabolite

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9
Q

Gemcitabine (Gemzar)

A

Antimetabolite

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10
Q

6- Mercaptopurine

A

Purine analogs (Antimetabolite)

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11
Q

Fludarabine

A

Purine analogs (Antimetabolite)

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12
Q

Cladribine

A

Purine analogs (Antimetabolite)

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13
Q

Pentostatin

A

Purine analogs (Antimetabolite)

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14
Q

6-Thioguanine

A

Purine analogs (Antimetabolite)

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