Miscellaneous Tests Flashcards
1
Q
What is a normal ejection fraction?
A
50-70%
2
Q
What is an EF of under 40%?
A
HF or cardiomyopathy
3
Q
What do positive CD34, TDT, PAX5, and CD10 in a bone marrow biopsy correlate with?
A
immature B-cell lymphoblastic leukemia/lymphoma
4
Q
What is a positive BCR-ABL significant for?
A
Chronic myelogenous lymphoma (usually); also associated with ALL
5
Q
Reciprocal translocation that results in BCR-ABL is known as the ________ _________.
A
Philadelphia Chromosome
6
Q
What kind of anti-neoplastic drug would you want to add to treat leukemia if you have a positive BCR-ABL?
A
Tyrosine kinase inhibitor (TKI) must be added to the treatment regimen
7
Q
An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it.
A
BCR-ABL translocation (Philadelphia chromosome)
