Miscellaneous Flashcards

1
Q

What is the best test on physical exam to rule out mononucleosis?

A

Absence of lymphadenopathy

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2
Q

What is the definition of fever of unknown origin?

A

Temperature > 38.3 over 3 weeks with 1 week of investigation.

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3
Q

What is Q-fever?

A

Infection caused by Coxiella burnetti

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4
Q

What is the reservoir for Coxiella burnetti?

A

Ticks, but the most common cause of infection is farm animals. Living down-wind from a farm or working in a slaughterhouse is also a risk factor.

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5
Q

When would you consider PCP prophylaxis in the setting of steroid use?

A

If you are planning to treat someone else with prednisone > 20 mg/d for > 4-8 weeks

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6
Q

How do you screen for strongyloides?

A

Screen with serology +/- stool ova and parasites

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7
Q

Who would you screen for strongyloides?

A

Patients who are or are going to be immunosuppressed and have either lived in or had extended travel to an extended area.

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8
Q

In what regions is strongyloides endemic?

A

Rural areas of tropical and subtropical regions - SE Asia, Western Pacific, Latin America & Carribean

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9
Q

What is larva currens?

A

Raised, pink, pruritic streaks along the trunk, thighs and buttocks that result from larvae migrating in subcutaneous tissues.

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10
Q

What are the clinical manifestations of a strongyloides infection?

A

(1) Irritation at the site of skin penetration, including urticaria and edema.
(2) Dry cough and wheeze
(3) GI Symptoms: diarrhea, constipation, abdominal pain, anorexia

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11
Q

Which species of Candida is resistant to echinocandins?

A

C. Parapsilosis

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12
Q

Which species of candida are resistant to fluconazole (2)?

A

C. Galbrata

C. Krusei

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13
Q

Which antifungal do you need to use for empiric coverage of Candida species in pregnancy?

A

Amphotericin B

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14
Q

What is the treatment for invasive aspergillosis?

A

Voriconazole for at least 6 weeks

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15
Q

What are the highrisk blood borne pathogen exposures (4)?

A

Blood
Semen
Vaginal Secretions
Visceral Fluid (pleural, peritoneal, pericardial, amniotic)

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16
Q

What injuries are high risk for bloodborne pathogen exposure?

A

Percutaneous (large hollow bore needles)

17
Q

What is the management for HIV post-exposure prophylaxis from a bloodborne pathogen?

A

Truvada PLUS dolutegravir (or raltegravir) x 28 days if presenting within 72 hours of the exposure

18
Q

If you were exposed to a patient with hepatitis C through needle stick injury or other route, what is the management?

A

No prophylaxis

Repeat testing in 4-6 months