Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infectious Disease > GU & STI Infections > Flashcards

GU & STI Infections Flashcards

1
Q

What are the first line treatment options for uncomplicated cystitis?

A

Nitrofurantoin 100 mg PO BID x 5d (not in pyelonephritis)
Septra 1 DS Tab BID x 3 days
Fosfomycin 3 g sachet x 1 (not in pyelo)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the options for treatment of pyelonephritis?

A

Beta-lactam (CTX) x 1-2 weeks

Fluoroquinolone x 5-7d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

When is screening and treatment for asymptomatic bacteruria recommended?

A

Pregnancy

Invasive Urological Procedures (endoscopic with mucosal damage)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the treatment for Chlamydia?

A

Azithromycin 1 gram PO x 1 OR

Doxy 100 mg PO BID x 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the treatment for gonorrhea?

A

Ceftriaxone 250 mg IM x 1 AND

Azithromycin 1 gram PO x 1 (to cover Chlamydia as well)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How is neurosyphilis treated?

A

Aqueous penicillin 4mU q4 hrs IV x 14 days, then Benzathine Pen G 2.4 MU IM x 1 if possible late latent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How would you treat late latent & tertiary syphilis?

A

Benzathine Pen G 2.4 MU IM weekly x 3 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How would you treat primary, secondary or early latent syphilis?

A

Benzathine Pen G 2.4 MU IM x 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is tabes dorsalis?

A

Locomotor ataxia caused by syphilis due to damage of the dorsal columns and roots of the spinal cord.

Characterized by:

  • Sensory Ataxia
  • Areflexia
  • Lancinating Pains
  • Pupillary Abnormalities (Argyll-Robertson pupil)
  • Urinary Retention
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is an Argyll-Robertson pupil?

A

A small pupil that odes not react to light but can accommodate and coverage normally.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is defined as treatment failure of Chlamydia and Gonorrhea?

A

Positive Gram stain > 72 hrs after tx
Positive Cx > 72 hours after tx
Positive NAAT 2-3 weeks after tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When is test of cure indicated for gonorrhoea and chlamydia infection?

A

Gonorrhoea: ALL infections
Chlamydia: Sub-optimal compliance, unresolved symptoms, pregnancy, pre-puberty OR alternative Rx used.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the incubation period and manifestations of primary syphilis?

A

Within 3 weeks

Painless chancre, regional LN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the manifestation of secondary syphilis?

A 
Constitutional - Fever, malaise
Rash
Alopecia
Uveitis
Meningitis
Lymphadenopathy 
Hepatitis 
Arthralgia
Condylomata Lta
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the definition of early and late latent syphilis?

A

No Clinical Manifestations

Early < 1 year
Late > 1 year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the non-treponemal tests?

A

VRDL

RPR (rapid plasma reagin)

17
Q

What are the indications in syphilis for penicillin desensitization in the setting of allergy?

A

Neurosyphilis
Pregnancy
Late Latent or Unknown Duration
Tertiary Syphilis

18
Q

What are the indications for LP in syphilis?

A
  1. Neurological, ocular or auditory symptoms.
  2. HIV & Neuro signs/symptoms
  3. Previously treated but failed to achieve adequate serological response to treatment.
19
Q

What causes Chancroid?

A

H. ducreyi

20
Q

How does chancroid present?

A

Painful ulcer with granulomatous base that bleeds and is associated with painful lymphadenopathy.

21
Q

How do you treat chancroid?

A

Ciprofloxacin 500 mg PO x 1 dose OR

Azithromycin 1 g PO x 1 dose

22
Q

How do you treat bacterial vaginosis?

A

Metronidazole 500 mg PO BID x 7 days

23
Q

What STI classically causes a “strawberry cervix”?

A

Trichomonas vaginalis

24
Q

With which STI do you see clue cells on gram stain?

A

Bacterial vaginosis

25
Q

What makes a UTI “complicated”(6)?

A

(1) Hemodynamic Instability
(2) Male
(3) Pregnancy
(4) Indwelling Foley or Instrumentation
(5) Functional or Anatomic Anomalies
(6) Urinary Tract Obstruction

26
Q

What is the preferred treatment for pyelonephritis in pregnancy?

A

IV beta-lactate for 7-14 days

27
Q

What is the empiric treatment for postpartum endometritis?

A

Empiric treatment with clindamycin and an aminoglycoside (+/- ampicillin or vancomycin if enterococcus suspected).

28
Q

What is the empiric treatment for prostatitis?

A

(1) Well —> Fluoroquinolone (FQ)
(2) Unwell —> Empiric piptazo, third generation cephalosporin OR FQ

Pathogen directed therapy on culture results.
Acute Prostatitis Duration: 2-4 weeks
Chronic Prostatitis Duration: 4-6 weeks for FQ, 8-12 weeks if other abx

29
Q

How would you treat a disseminated gonococcal infection/arthritis?

A

Ceftriaxone 2 grams IV/IM daily x 7 days minimum - would still add azithromycin to cover for undiagnosed Chlamydia AND to ensure that gonorrhea is covered.

30
Q

What are the indications for penicillin desensitization in the treatment of syphilis (3)?

A

(1) Neurosyphilis
(2) Pregnancy
(3) Late latent, latent of unknown duration or tertiary syphilis.

31
Q

What is the inguinal syndrome in lyphogranuloma venereum?

A

Secondary infection 2-6 weeks after the initial inoculation, with local/direct extension into the region lymph nodes (inguinal/femoral), which grow quite large and can rupture (“groove sign”).

32
Q

What is Fitz-Hugh-Curtis syndrome?

A

Inflammation of Glisson’s capsule around the liver, most commonly with Gonorrhoea infection (“gonococcal peri hepatitis”).

33
Q

What is an alternative treatment for gonorrhoea in someone who is allergic to penicillin?

A

(1) Azithromycin 2g PO
PLUS one of:
(A) Gentamicin 240 mg IV/IM x 1 OR
(B) Ciprofloxacin 500 mg PO x 1

34
Q

What are 3 alternative treatments for primary, secondary or early latent syphilis if a patient is allergic to penicillin?

A

(1) Azithromycin 2 g x 1 dose
(2) Doxycycline 100 mg BID x 14 days
(3) Tetracycline 500 mg QID x 14 days

35
Q

What do you see on biopsy of LGV?

A

Mimics IBD on biopsy with:
Crypt abscesses
Granulomas
Giant cells

36
Q

How do you treat Trichomonas vaginalis?

A

Metronidazole 2g PO x 1 or 500 mg PO x 7 days

Infectious Disease (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions