Miscellaneous Flashcards
1
Q
Achalasia Selective loss of \_\_\_\_ neurons to LOS Loss of what function Mean age Symptoms
A
Post synaptic inhibitory neurons to LOS
Peristalsis
9 years
Dysphagia, halitosis, respiratory Sx, under nutrition
2
Q
Caustic ingestion Alkali or acid more common? Alkaline causes what injury Complications Immediate (2) Longterm (1)
A
Alkali Liquefaction necrosis Haemorrhage RDS Stricture (20%)
3
Q
Most common cause chronic pancreatitis 1st world 3rd world (3) syndromes (2) endocrine (1) parasite
A
CF Malnutrition Schwannman-Diamond Pearson Hereditary Pancreatitis (AD, variable expression) Hyperlipidemia Hyper parathyroidism Ascariasis
4
Q
Schwachmann Diamond
Triad
Pancreatic acini replaced by
Onset of symptoms
Symptoms of
A
Exocrine pancreatic insufficiency
(2nd most common after CF)
Metaphyseal dysostosis- Short stature & delay
Cyclical neutropenia +- pan cytopenia
Infancy & early childhood
Malabsorption, steatorrhoea, abdo distension, FTT
Neutropenia (95%)
SS, syndactyly
5
Q
Hereditary pancreatitis Inheritance Cationic \_\_\_\_ gene allows \_\_\_\_\_\_\_\_ Episodes start Longterm complications
A
AD Cationic trypsinogen gene Autodigestion First decade Pseudocysts Exocrine insufficiency Calcification
6
Q
Pearson syndrome
____ DNA mutation
Features (3)
A
Sporadic mitochondrial DNA Severe macrocytic anaemia Thrombocytopenia Ringed sideroblasts on BMA Growth failure -pancreatic insufficiency
7
Q
Chemotherapy causing pancreatitis
Antibiotics causing pancreatitis
A
L-asparaginase
6-MP
Vincristine
Erythromycin
Sulfonamides
Tetracyclines
8
Q
Infections causing pancreatitis
A
EBV, measles, mumps, influenza, rubella Ascariasis Leptospirosis Malaria Mycoplasma
9
Q
H pylori Gram \_\_\_ shape? Produces \_\_ Which produces \_\_\_\_ Associated with (3) % adolescents in developed countries Causes what % duodenal, % gastric ulcers
A
Gram neg curved rod Urease which produces ammonia, neutralises acid Allows bacteria to bury into epithelium 10% adolescents 90% duodenal 70% gastric
Associated with blood group O
10
Q
CD25
What
Elevated in which condition
A
Soluble IL-2 receptor
HLH
