Jaundice

Question 1

Breast-milk jaundice

• frequency
• develops when
• jaundice peaks when , can last for __
• diagnosis supported by __

Answer 1

0.5-2%
Develops after day 4 or day 7
Jaundice peaks end of week 2
Can last for 1-2 months
Dx supported by drop in SBR >50% if breastfeeding disrupted by 48h

Question 2

Gilbert
Frequency
Deficiency of
Chromosome
Presents as
Management

Answer 2

7%
Mild deficiency of UGT activity 
2q37
Higher incidence of neonatal jaundice & BM jaundice, usually presents after puberty incidentally or jaundice after fasting or intercurrent illness 
No treatment required

Question 3

Biliary Atresia 
Incidence
Uss findings
Most common complication
% requiring liver transplantation by 20y
Need to supplement \_\_

Answer 3

1 per 16,000
Absent gallbladder or irregular outline & triangular cord sign
Ascending cholangitis 45-50% in 1st year
80%
Fat soluble vitamin