Miscellaneous

Question 1

6 factors in evaluating rheumatology cases?

Answer 1

1. articular? (in a joint?)
2. acute or chronic
3. inflamamtory?
4. distribution/demographic
5. pattern
6. symmetrical?

Question 2

rheumatology

Answer 2

study of disease of joints

Question 3

swelling and pain in fingers, three years, worsens through day, symmetric in PIPs and DIPs, NON inflammatory

Answer 3

osteoarthritis

Question 4

PIPs and DIPs pain, IS INFLAMMATORY, chronic

Answer 4

rheumatoid arthritis

Question 5

what are the crystal forming diseases?

Answer 5

gout
CPPD
pseudogout

Question 6

osteoarthritis is primarily a disease of______

Answer 6

cartilage -

Question 7

asymmetric cartilage loss

Answer 7

osteoarthritis

Question 8

rheumatoid arthritis is primarily a disease of ___

Answer 8

bone

Question 9

extremity bends away from midline

Answer 9

valgus

Question 10

bends toward midline

Answer 10

varus

Question 11

morning stiffness is less than 30 min; more than that

Answer 11

osteoarthritis; inflammatory arthritis

Question 12

worse with activity

Answer 12

osteoarthritis

Question 13

better with activity

Answer 13

RA

Question 14

acute intermittent arthritis, mono arthritis, asymmetric, very high wbc and high esr, pain of several joints

Answer 14

peudogout

Question 15

women vs men - who gets tumors in bones more easily vs arthritis

Answer 15

women - arthritis

men - tumors

Question 16

CPPD

Answer 16

calcium pyrophostphate dihydrate in cartilage

Question 17

calcification in cartilage

lab: Ca, Mg, ferritin, Iron

Answer 17

CPPD

Question 18

how to treat CPPD?

Answer 18

corticosteroid injection

Question 19

gout vs pseudogout site of infection

Answer 19

gout - smaller distal joints (ankle, phalanges, olecranon etc)
pseudogout larger proximal (knee, back wrist)

Question 20

urate in serum

Answer 20

gout

Question 21

yellow needle like vs blue rhomboid like

CRYSTALS

Answer 21

yellow needleis gout and blue rhomboid is pseudogout

Question 22

RA: which is first, skin or bone?

Answer 22

skin

Question 23

sausage digits

Answer 23

reactive or psoriatic arthritis

Question 24

multinucleate and resorbs bone

Answer 24

osteoclast

Question 25

mononuclear in stroma, usedto be osteoblasts

Answer 25

osteocytes

Question 26

woven bone

Answer 26

produced rapidly (fetal/fracture repair), haphazard collagen fibers, less sturdy, ALWAYS PATHOLOGIC IN ADULTS

Question 27

osteoblastic rimming

Answer 27

mononucleate cells around surface of bone being produced

Question 28

synovial fluid analysis:
if infectious?
if gout?
if pseudogout?

Answer 28

infection - neutrophils
gout - needles
pseudogout - rhomoids

Question 29

OA vs RA - hand joints

Answer 29

oa is more distal

ra is more proximal (MCP)

Question 30

fast growing tumor (onion skin) with low mitotic index

Answer 30

ewing sarcoma

Question 31

what differentiates PNET from ewing sarcoma?

Answer 31

homer wright rosettes

Question 32

RANKL

Answer 32

protein on osteoblasts that activates osteoclasts!