Miscellaneous Flashcards

1
Q

6 factors in evaluating rheumatology cases?

A
  1. articular? (in a joint?)
  2. acute or chronic
  3. inflamamtory?
  4. distribution/demographic
  5. pattern
  6. symmetrical?
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2
Q

rheumatology

A

study of disease of joints

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3
Q

swelling and pain in fingers, three years, worsens through day, symmetric in PIPs and DIPs, NON inflammatory

A

osteoarthritis

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4
Q

PIPs and DIPs pain, IS INFLAMMATORY, chronic

A

rheumatoid arthritis

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5
Q

what are the crystal forming diseases?

A

gout
CPPD
pseudogout

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6
Q

osteoarthritis is primarily a disease of______

A

cartilage -

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7
Q

asymmetric cartilage loss

A

osteoarthritis

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8
Q

rheumatoid arthritis is primarily a disease of ___

A

bone

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9
Q

extremity bends away from midline

A

valgus

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10
Q

bends toward midline

A

varus

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11
Q

morning stiffness is less than 30 min; more than that

A

osteoarthritis; inflammatory arthritis

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12
Q

worse with activity

A

osteoarthritis

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13
Q

better with activity

A

RA

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14
Q

acute intermittent arthritis, mono arthritis, asymmetric, very high wbc and high esr, pain of several joints

A

peudogout

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15
Q

women vs men - who gets tumors in bones more easily vs arthritis

A

women - arthritis

men - tumors

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16
Q

CPPD

A

calcium pyrophostphate dihydrate in cartilage

17
Q

calcification in cartilage

lab: Ca, Mg, ferritin, Iron

18
Q

how to treat CPPD?

A

corticosteroid injection

19
Q

gout vs pseudogout site of infection

A

gout - smaller distal joints (ankle, phalanges, olecranon etc)
pseudogout larger proximal (knee, back wrist)

20
Q

urate in serum

21
Q

yellow needle like vs blue rhomboid like

CRYSTALS

A

yellow needleis gout and blue rhomboid is pseudogout

22
Q

RA: which is first, skin or bone?

23
Q

sausage digits

A

reactive or psoriatic arthritis

24
Q

multinucleate and resorbs bone

A

osteoclast

25
mononuclear in stroma, usedto be osteoblasts
osteocytes
26
woven bone
produced rapidly (fetal/fracture repair), haphazard collagen fibers, less sturdy, ALWAYS PATHOLOGIC IN ADULTS
27
osteoblastic rimming
mononucleate cells around surface of bone being produced
28
synovial fluid analysis: if infectious? if gout? if pseudogout?
infection - neutrophils gout - needles pseudogout - rhomoids
29
OA vs RA - hand joints
oa is more distal | ra is more proximal (MCP)
30
fast growing tumor (onion skin) with low mitotic index
ewing sarcoma
31
what differentiates PNET from ewing sarcoma?
homer wright rosettes
32
RANKL
protein on osteoblasts that activates osteoclasts!