Miscellaneous 2 Flashcards
4 stages of bone healing
- Inflammation
- Soft callus
- Hard callus
- Remodeling
Inflammation
- Peaks at 48 hours, subsides at 1 week
- Inflammation acts as an immoblizer by causing pain and edema
4 days
Soft callus
- Begins several days after injury and persists for 1-2 months
- Fibrous and cartilagenous tissue develops at each end of the fracture
- If the soft callus fails to unite, the two sides of the fracture will cease to grow and will be resorbed
4 weeks
Hard callus
If a soft callus is successful in connecting the fracture, it begins to ossify
- This occurs at 2-4 months
4 weeks
Remodeling
- Lasts for several years
- Excessive callus is resorbed
- Final bone morphology is determined by Wolff’s law
4-ever
How long does it take for osteomyelitis to show up on x-ray?
2 weeks
Osteomyelitis takes about 2 weeks to show up on x-ray after there has been a 50% loss of bone
Sequestrum
A piece of necrotic bone separated from living bone by granulation tissue, radiographically evident as a highly opaque, smooth island of bone that is usually surrounded by areas of decreased bone density
Involucrum
A layer of living bone that has formed around the dead (infected) bone
Cloaca
An opening in the involucrum that may form a sinus and drain
Brodie’s abscess
A chronic abscess in bone surrounded by dense fibrous tissue and sclerotic bone, most commonly found in the metaphysis
Phases of wound healing
- Inflammatory phase
- Proliferative phase
- Remodeling phase
Inflammatory phase
- 1-7 days
- Influx of platelets and leukocytes
- Release of cytokines and mediators
- Coagulation
Proliferative phase
- 5-20 days
- Collagen fibers are produced and lend strength to wound
- Re-epithelialization (some authors describe epithelialization as a separate phase between proliferation and remodeling)
- Angiogenesis
- Fibroplasia
- Wound contraction
Remodeling phase
AKA maturation
- 3 weeks to 2 years
- Deposition of matrix materials
- Collagen deposition/remodeling
- Return to preinjury state
- As long as the scar or past ulcer site is erythematous, remodeling is occurring
Stages of Charcot
- Stage 0: Pre-Charcot
- Stage 1: Fragmentation/developmental
- Stage 2: Coalescence
- Stage 3: Remodeling/reconstruction
Stage 0
Pre-Charcot
- Warmth, dull pain, swelling and joint instability, with normal appearing bone and joints on radiographs
- Acute sprain or fracture in the presence of neuropathy
Stage 1
Fragmentation or developmental
- Clinical signs and symptoms of inflammation (warmth, erythema and edema)
- X-ray: bone debris formation at the articular margins, fragmentation of the subchondral bone, subluxation, dislocation and capsular distention
- Dissolution, fragmentation, dislocation
Stage 2
Coalesence
- Beginning of the reparative process
- Edema, warmth and redness diminish
- X-ray: absorption of fine debris and fusion of large fragments to adjacent bones, bone ends become sclerotic
Stage 3
Remodeling/reconstruction
- Bony consolidation and healing
- Residual bony deformity is common, most notably collapse of the longitudinal arch resulting in the classic “rocker-bottom” foot
- Rounding of the bone ends with a decrease in sclerosis
- Bony protuberences are clinically important because they may develop sites for future neuropathic pressure ulcers
HBO therapy
- Increases oxygen concentration in the blood
- Angiogenesis and fibroblast production occurs, which helps with collagen synthesis and epithelial closure
- During HBO treatment and for 3-4 HOURS AFTER the O2 is dissolved in the plasma and helps oxygenate the hypoxic area
- Speeds healing time for ulcerations
Baxter’s neuritis
- Entrapment neuropathy of the 1st branch of the lateral plantar nerve (AKA nerve to abductor digiti minimi muscle)
- Pain after activity rather than pain first thing in the morning as with plantar fasciitis
Pigmented villonodular synovitis
- Symptoms: pain, joint effusion, hemarthrosis (thus hemosiderin pigment), limited ROM
- The syovium will appear red-brown in color due to the hemosiderin found in the tissue