miscellaneous Flashcards
what is the function of iL-1
pyrogen
also calld osteoclast actiating fato
function of IL 2 ?
stimulates T cells
function of IL 3 ?
stimulates bone marrow stem cells
GM-CSF
function of IL 4 ?
helps for the differentiation into Th2
stimulates IgE production
maturation of B cells
function of IL 5 ?
stimulates IgA production
B cell differentiation
differentiation of eosinophils
function of IL 6 ?
stimulates the liver too create acute phase proteins
what is the mnemonic for IL 1 to 6 ?
HOT T BONE stEAK
function of IL 8 ?
chemotaxis for neutrophils
function of IL 10 ?
decrease thee expression of MHC 2 and TH1
what are the cytokines that attenuate the immune response ?
TGF beta
L 10
Trgg
function of IL 12 ?
diffreentiiation ooff t cells into Th1
activation of NK cells
function of IL 13 ?
IgE prroductionn
which cytokines are produced by macrophages ?
IL 1
IL 6
IL 8
IL 12
TNF alpha
which cytokines are produced by Th1 ?
INF gamma
which cytokines are produced by Th2 ?
IL 4 , IL 5, Il 10, IL 13
what are the CD fo B cells ?
D 19 , 20 , 21
whicch CD is used by EBV to enter B cells ?
CD21
which CD is expressed by macrophages ?
CD14, CD40
what is the D on hematopoeitic cells ?
CD 34
mnemonic for live attenuated vaccines ?
attention teachers please vaccinate young beautiful small infants with MMR regularly
Adenovirus
Typhoid
Polio
Varicella
yellow fever
BCG
smallpox
influenza oral
MMR
what type of immune response is associated with live attenuated vaccines ?
cell mediated iimmunity.
what type of immunity is associated with killed vaccine ?
humoral response
mnemonic for killed vaccines ?
A TRIP could Kill you
Hepatitis A
Typhoid
Rabies
Influenza
Polio
What is the means of acquisition for passive immunity?
Receiving preformed antibodies.
What is the means of acquisition for active immunity?
Exposure to exogenous antigens.
How quickly does passive immunity onset?
Rapid.
How quickly does active immunity onset?
Slow
How long does passive immunity last?
Short span of antibodies (half-life = 3 weeks).
How long does active immunity last?
Long-lasting protection (memory).
Give examples of passive immunity.
IgA in breast milk, maternal IgG crossing the placenta, antitoxin, humanized monoclonal antibody
Give examples of active immunity.
Natural infection, vaccines, toxoid.
What is a special note about IVIG in passive immunity?
IVIG and other immune globulin preparations can provide temporary but specific passive immunity to a target pathogen
When are combined passive and active immunizations given?
For hepatitis B or rabies exposure.
