miscellaneous Flashcards

1
Q

what is the function of iL-1

A

pyrogen
also calld osteoclast actiating fato

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2
Q

function of IL 2 ?

A

stimulates T cells

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3
Q

function of IL 3 ?

A

stimulates bone marrow stem cells
GM-CSF

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4
Q

function of IL 4 ?

A

helps for the differentiation into Th2
stimulates IgE production
maturation of B cells

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5
Q

function of IL 5 ?

A

stimulates IgA production
B cell differentiation
differentiation of eosinophils

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6
Q

function of IL 6 ?

A

stimulates the liver too create acute phase proteins

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7
Q

what is the mnemonic for IL 1 to 6 ?

A

HOT T BONE stEAK

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8
Q

function of IL 8 ?

A

chemotaxis for neutrophils

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9
Q

function of IL 10 ?

A

decrease thee expression of MHC 2 and TH1

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10
Q

what are the cytokines that attenuate the immune response ?

A

TGF beta
L 10
Trgg

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11
Q

function of IL 12 ?

A

diffreentiiation ooff t cells into Th1
activation of NK cells

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12
Q

function of IL 13 ?

A

IgE prroductionn

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13
Q

which cytokines are produced by macrophages ?

A

IL 1
IL 6
IL 8
IL 12
TNF alpha

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14
Q

which cytokines are produced by Th1 ?

A

INF gamma

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15
Q

which cytokines are produced by Th2 ?

A

IL 4 , IL 5, Il 10, IL 13

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16
Q

what are the CD fo B cells ?

A

D 19 , 20 , 21

17
Q

whicch CD is used by EBV to enter B cells ?

A

CD21

18
Q

which CD is expressed by macrophages ?

A

CD14, CD40

19
Q

what is the D on hematopoeitic cells ?

A

CD 34

20
Q

mnemonic for live attenuated vaccines ?

A

attention teachers please vaccinate young beautiful small infants with MMR regularly
Adenovirus
Typhoid
Polio
Varicella
yellow fever
BCG
smallpox
influenza oral
MMR

21
Q

what type of immune response is associated with live attenuated vaccines ?

A

cell mediated iimmunity.

22
Q

what type of immunity is associated with killed vaccine ?

A

humoral response

23
Q

mnemonic for killed vaccines ?

A

A TRIP could Kill you
Hepatitis A
Typhoid
Rabies
Influenza
Polio

24
Q

What is the means of acquisition for passive immunity?

A

Receiving preformed antibodies.

25
Q

What is the means of acquisition for active immunity?

A

Exposure to exogenous antigens.

26
Q

How quickly does passive immunity onset?

A

Rapid.

27
Q

How quickly does active immunity onset?

A

Slow

28
Q

How long does passive immunity last?

A

Short span of antibodies (half-life = 3 weeks).

29
Q

How long does active immunity last?

A

Long-lasting protection (memory).

30
Q

Give examples of passive immunity.

A

IgA in breast milk, maternal IgG crossing the placenta, antitoxin, humanized monoclonal antibody

31
Q

Give examples of active immunity.

A

Natural infection, vaccines, toxoid.

32
Q

What is a special note about IVIG in passive immunity?

A

IVIG and other immune globulin preparations can provide temporary but specific passive immunity to a target pathogen

33
Q

When are combined passive and active immunizations given?

A

For hepatitis B or rabies exposure.