Miscellaneous Flashcards
Arsenic sources (3) + treatment (2)
Pesticides, contaminated water (I.e wells), pressure-treated wood; Dimercaprol British, DMSA succimer
Substances causing methemoglobinemia (3) + treatment (2)
dapsone, nitrites, local/topical anesthetics; methylene blue or vitamin C
How long after ingestion can you give activated charcoal
~1-2 hours up to 4
What is sarin, soman, and tabun?
Organophosphate chemical weapons that have a slightly fruity smell
What is a Geiger-Müller counter?
Detects radiation exposure
Snake bite treatment and indication
Crotalidae polyvalent immune Fab (FabAV); only for people with symptoms, abnormal coagulation, or cardiovascular compromise as it can cause severe anaphylaxis
Treatment for decompression sickness
IV fluids, 100% oxygen and hyperbaric oxygen therapy
Treatment of High Altitude Cerebral Edema (HACE)
Dexamethasone
When to give activated charcoal for acetaminophen OD
> 7.5g ingested, 4 hours or less of ingestion
Normal post-void residual; Post-void residual in overflow incontinence; post-void in urge incontinence
<100ml; >200ml; <50ml
Lab changes in Cushings
Hypertension, Hyperglycemia, Hypernatremia, Hypokalemia
Renal blood flow (RBF) formula
RPF/(1-Hct); RBF usually 20-25% of cardiac output
Renal plasma flow (RPF) formula
UV/P of PAH
Filtration fraction (FF) formula; Normal FF?
GFR/RPF; Normal: 20%
Filtered load (mg/min) formula
GFR x plasma concentration
Treatment for Stable Ectopic Pregnancy
Methotrexate
Treatment for unstable Ectopic pregnancy
Surgery
Other name for teratoma
Dermoid tumour
Parkland Formula for fluid resuscitation in burns
4mL x body weight (kg) x TBSA (%)= total crystalloid fluids in first 24 hours
Half total volume in first 8 hours, half given over following 16 hours
CCB that can be used in heart failure
Amlodipine
Chromium deficiency manifestation (1)
Impaired glucose control
Copper deficiency manifestation (3)
Brittle hair
Skin depigmentation
Neurological dysfunction
Selenium deficiency manifestation (3)
Thyroid dysfunction
Cardiomyopathy
Immune dysfunction
Zinc deficiency manifestation (5)
Alopecia
Pustular skin rash
Hypogonadism
Impaired wound healing
Impaired taste
Niacin deficiency manifestation (3)
Dermatitis
Diarrhea
Dementia
Entamoeba Tx
Metronidazole/Tinidazole PLUS Paromomycin
Adolescent Idiopathic Scoliosis dx tests; Risk factors for curve progression (5)
Unilateral thoracic/lumbar prominence on forward bend test. Cobb angle >10 degrees consistent with scoliosis, >25 degrees is severe.
“SAFES”
Skeletal immaturity, Age <12, Female, Early puberty, Severe curvature >25
Legionnaires Disease features
Atypical pneumonia, confusion, GI features, hyponatremia, bradycardia
Differentiation b/w Vascular Dementia and Alzheimer’s
Vascular dementia will have executive dysfunction rather than memory loss. Urinary and reflex abnormalities are moreso seen in vascular dementia
JVP Waveform correlations (A, C, x, V, y)
A: Atrial contraction
C: Ventricular contraction
x: Atrial relaxation
V: Maximal atrial filling
y: Atrial emptying
What can cause pulsus paradoxus? (3)
Decrease in Blood Pressure >10mmHg during inhalation
-Cardiac tamponade, asthma, COPD
Rituximab to treat which leukemia?
Chronic lymphocytic leukemia (CLL)
Imatinib is used to treat which leukemia?
Chronic myeloid leukemia (CML)
Cytarabine used to treat which leukemia?
Acute Myeloid Leukemia (AML)
Treatment for Acute Lymphoblastic Leukemia (ALL)
Hyper-CVAD
-Cyclophosphamide, vincristine, doxorubicin (Adriamycin), Dexamethasone
Adverse effects of each DMARD (Methotrexate, Leflunomide, Hydroxychloroquine, Sulfasalazine, TNFa-inhibitors)
Methotrexate: Hepatotoxicity, stomatitis, cytopenias
Leflunomide: Hepatotoxicity, cytopenias
Hydroxychloroquine: Retinopathy
Sulfasalazine: Hepatotoxicity, stomatitis, hemolytic anemia
TNFa-inhibitors: infection, demyelination, CHF, malignancy
Drug of choice for small intestinal bacterial overgrowth (SIBO)
Rifaximin
What is a Gastric Bezoar?
Accumulation of undigestible materials (hair, foreign objects) in stomach; leads to gastric outlet obstruction (GOO)
What is a succussion splash?
Splash sound heard when abdomen is rocked from retained food in stomach, heard in gastric outlet obstruction (GOO)
What is a trachoma?
Bacterial conjunctivitis caused by Chlamydia
Causes of Osteonecrosis (avascular necrosis)
“CAST Bent LEGS” - Corticosteroids, Alcoholism, Sickle cell, Trauma, Bend (decompression), LEgg-Calve-Perthes, Gaucher, Slipped capital femoral epiphysis
Aflatoxin increases risk of which malignancy?
Hepatocellular Carcinoma
Bordetella Pertussis Tx
Macrolide (Azithromycin, Clarithromycin)
Ogilvie Syndrome causes (6) and treatment (2)
Causes: Major surgery, injury, infection, electrolyte derangement, medication (opiates, anticholinergic), neurological disorders
Treatment: NG/rectal decompression. Neostigmine if no improvement within 48hrs
Antibody associated with Autoimmune Pancreatitis
Immunoglobulin G4 (IgG4)
Most specific antibody for Autoimmune Hepatitis
Anti-Liver Kidney Microsomal Antibody (Anti-LKM-1); other antibodies are ANA and anti-smooth muscle
Skin infection associated with Parkinson’s + Cause + Treatment
Seborrheic Dermatitis; Malassezia; Topical Ketoconazole
Chest XRay findings in pulmonary embolism (3)
Westermark sign: Peripheral hyperlucency of pulmonary arterial tree
Hampton hump: Peripheral, wedge-shaped opacity representing infarction
Fleischner sign: Enlargement of pulmonary artery
What is Hyposthenuria? What condition is it associated with
Kidneys unable to concentrate urine resulting in abnormally low specific gravity; Associated with Sickle Cell Disease
Treatment of Postherpetic Neuralgia (PHN)
-Anticonvulsants (Gabapentin, Pregabalin)
-TCAs (Amitriptyline, Desipramine, Nortriptyline)
-Topical Capsaicin
How to differentiate Biliary Colic from Acute Cholecystitis
Biliary colic has quick resolution and lack of fever, abdominal tenderness, and leukocytes which helps distinguish it from cholecystitis
Imaging modality for pancreatic tumor in head vs body/tail
Head: Ultrasound
Body/tail: Abdominal CT scan
Antibody & MSK pathology associated with PBC and treatment
Antimitochondrial antibody ; Osteoporosis/Osteomalacia ; Ursodeoxycholic acid
Cause of pill esophagitis (other than tetracycline or bisphosphanates)
NSAIDS, iron, and potassium chloride
Pancreatitis causes (11)
“I GET SMASHED”
I- Idiopathic
G- Gallstones (2nd most common cause)
E- Ethanol (most common cause)
T- Trauma
S- Steroids
M- Mumps/Malignancy
A- Autoimmune (IgG4)
S- Scorpion
H- Hypertriglyceride (>1000) or Calcium
E- ERCP
D- Drugs (HCTZ, Didanosine, Pentamidine, Bactrim, Azathioprine)
Findings on slit-lamp for keratitis (bacteria vs HSV vs fungi)
Bacteria: Central, round ulcer
HSV: Branched, dendritic ulcers
Fungi (i.e., candida): Ulcers with feathery margins
Hepatopulmonary syndrome pathology and clinical findings
Intrapulmonary vascular dilations in setting of chronic liver disease; Platypnea (dyspnea when upright) and orthodeoxia (oxygen desat when upright)
Blood transfusion-related hypocalcemia
Increased citrate levels, binding calcium
Diagnosis/treatment of Upper Airway Cough Syndrome (UACS)(postnasal drip)
First-gen H1 receptor antagonists (I.e., chlorpheniramine)
Photosensitivity-causing drugs
“SAN LIGHT”
-Sulfonamides
-Amiodarone
-NSAIDS
-Loop diuretics
-Isotretinoin
-Griseofulvin
-Hydrochlorothiazide
-Tetracyclines
SJS-causing drugs
“SANA”
-Sulfonamides
-Anticonvulsants (I.e, lamotrigine)
-NSAIDS
-Allopurinol
MMR; precautions for each
Measles: Airborne
Mumps, Rubella: Droplet
Influenza and Pertussis precaution
Droplet
Tuberculosis precaution
Airborne
Varicella precaution
Airborne
What is seen in Felty Syndrome?
Rheumatoid arthritis, Neutropenia, Splenomegaly