Miscellaneous Flashcards
How is Well’s Criteria for Pulmonary Embolism scored?
Symptoms of DVT (+3)
No other likely Diagnosis (+3)
Heart Rate over 100 (+1.5)
Previous DVT/PE (+1.5)
Immobilization or surgery in last 4 weeks (+1.5)
Hemoptysis (+1)
active malignancy (+1)
Score of 0-1=low risk
2-6=Moderate Risk
7+= high risk
How is the Geneva Criteria for Pulmonary Embolism scored?
HR > 94 (+5) or 74-94 (+3)
Pain on LE deep venous palpation and unilateral edema (+4)
Previous DVT/PE (+3)
Unilateral LE pain (+3)
Surgery or Fracture within 1 month (+2)
Hemoptysis (+2)
Active Malignancy (+2)
Age over 65 (+1)
Score of 0-3=low risk
4-10=moderate risk
11 or higher=high risk
If there is no gap between fracture ends what kind of healing happens?
If there is <1mm of a gap how does this change the healing process?
How long is this healing process?
Primary or Direct Healing
if gap is <.01mm then cutting cones cross fracture line and osteoclasts come followed by osteoclasts to build new bone
If the gap is <1mm the gap is filled with perpendicular lamellar bone which will later be remodeled
Takes months to years
If there is a gap between fracture ends what type of healing takes place?
What are the different phases and the timeline for each phase?
Secondary or indirect fracture healing
Inflammatory Phase-Hematoma Forms (days 1-5)
Reparative Phase-Soft callus formation (days 4-14)
(angiogenesis, woven bone formed, chondrocytes replace clot with cartilage)
Modeling Phase-hard callus formation (weeks 2-3)
(cartilage calcifies, woven bone fills fracture line. Clinical union
Remodeling Phase-weeks 3-14
(osteoclasts/blasts remodel cartilage and woven bone into lamellar bone for up to one year after fracture)
What is Osteoarthritis?
What joints mostly get affected?
Degeneration of articular cartilage with changes to subchondral bone and synovium
large weight bearing joints asymmetrically
What are the distinguishing factors of OA over other forms of arthritis?
Asymmetrical
stiffness is less than 30 minutes in the morning
ROM improves quickly
MCPs are spared
What is Rheumatoid Arthritis?
What joints are mostly affected?
What are common related symptoms?
an auto-immune condition that causes primary tissue inflammation with remissions and exacerbations
smaller joints such as PIPs, and MCP joints
fever, fatigue, depression, weight loss, dry eyes, etc.
What are the distinguishing factors for rheumatoid arthritis over other arthritis type?
Symmetrical polyarthritis
stiffness over one hour
hot, doughy joint during flare ups
DIP’s spared
What is Ankylosing Spondylitis?
What joints are typically affected?
What is the common pain pattern?
chronic inflammatory disease that affects axial skeleton, eventually causing autofusion of vertebrae
symmetrical in SI joints and asymmetrical in periphery, mostly in spine joints and SI joints and occasionally in LE and shoulders
Pain is worse with rest and relieved with exercise, pain causes waking during the second half of the night
What are the distinguishing factors for ankylosing Spondylitis over other arthritis type?
young onset (less than 45 years old)
stiffness over 30 minutes
relieved with exercise
pain wakes during second half of night
What is Psoriatic Arthritis?
What joints are commonly affected?
autoimmune disease associated with the skin condition psoriasis
peripheral joints but particularly DIPs and the PIPs of hand and feet and SIJ bilaterally
What are the distinguishing factors for psoriatic arthritis over other arthritis type?
Psoriasis
Nail Lesions
Dactylitis
What are Fluoroquinolones medications?
What are common side effects?
What are some common brand names?
antibiotics that are associated with achilles tendon ruptures
Can cause ruptures and tendinopathies in other muscles including quads, patellar, wrist extensors, biceps, supraspinatus, etc
Also inhibits chondrocytes and can cause joint pain or muscle pain
ciprofloxacin (cipro)
What are Statin medications?
What MSK condition are they linked to?
Common brand names?
medication to treat hyperlipidemia
associated with tendinopathies and tendon ruptures, especially in achilles, quads, and distal biceps
also associated with rhabdomyolysis and myalgia usually in calves and thighs
atorvastatin (lipitor)
simvastatin
rosuvastatin (cipro)
What are glucocorticoids?
What common suffixes are associated with these medications?
What is long time oral use associated with?
corticosteroids
-methasone, -sonide, isone, etc.
if used over 3 months or more there is an associated risk with tendon ruptures especially in achilles, quads, and patellar; also can cause osteoporosis and spinal fractures