Misc Viruses

Question 1

Characteristics of Parvoviruses

Answer 1

DNA animal virus
ssDNA

Question 2

How do parvoviruses replicate

Answer 2

Autonomously in rapidly dividing cells

Question 3

What is the name of the parvovirus that infects humans

Answer 3

Parvovirus B19

Question 4

How is parvovirus transmitted

Answer 4

Body Fluids, Blood and Vertically from mother to fetus

Question 5

When do symptoms of parvovirus appear

Answer 5

4d to 2w after exposure

Question 6

clinical presentation of parvovirus

Answer 6

erythema infectiosum

1. viraemic phase
   - fever
   - malaise
   - myalgia
   - chills
   - itching
2. Immune Complex
   - rash
   -‘slapped cheeks’ appearance
3. targets erythroid progenitor celsl
   - lysis of cells = anemia

– pts with chronic hemolytic anemia & immunocompromised can cause aplastic anemia; pregnant pts can cause severe anemia in fetus (non-immune hydrops fetalis)