Misc MSK injury trigger Flashcards
MC in Children, esp males, in their metaphysis in long bones
hematogenous osteomyelitis
fever with bone pain and tenderness. Associated elevations in ESR, CRP and negative radiographs
osteomyelitis
may also see positive blood cultures!!
Urinary tract, skin/soft tissue, IV sites, endocardium, dentition are MC originations for what?
hematogenous osteomyelitis
MC in vertebral column LS>TS>CS in adults
hematogenous osetomyelitis
can be caused by prosthetic devices, neurosurgery, septic arthritis or open fractures/trauma
contiguous osteoarthritis
pt presenting with gradual onset of dull plantar foot pain and fever/chills 1 week ago. Ankle shows tenderness, warmth, erythema and swelling. what labs/imaging would you order in this patient? if imaging/labs are positive what would you see and what would be your next step?
suspected dx: osteomyelitis
labs: blood cultures (+), CBC (^WBC), ESR (^), CRP (^), BMP (just to assess renal/liver prior to meds)
Imaging: jump straight to MRI/CT d/t onset being <2 weeks and it being in the foot.
next step: consult ID/Ortho.
if + for staph start cefazolin, nafcillin or oxacillin (vanc for MRSA or PCN allergy) for 2 weeks followed by 4-6 wks of levo/cipro + rifampin
(slides say typically only use abx in long bone infections but i guess you could give abx)
Pt presents with 6 wk hx of localized pain over her lumbar area. pain is increased with percussion to the area. she has also been complaining of headaches and suffered a seizure en route to the hospital. what is your suspected dx? what imaging would you get in this patient?
osteomyelitis w vertebral involvement
remember neuro s/s can be seen in 1/3 of pts!
if you see neuro s/s you can jump straight to MRI/CT!
Xray shows loss of tissue planes and periarticular demineralization of bones
early osteomyelitis
Xray shows periosteal thickening or elevation and bone cortex irregularity
later osteomyelitis
if a pt has suspected osteomyelitis with radiologic evidence but their blood cultures are negative what is the protocol
bone biopsy
histology shows necrotic bone with extensive resorption adjacent to inflammatory exudate
osteomyelitis
(ceftaz/ceftriaxone/cefepime) + vanc is for what
empiric ABX for osteomyelitis (typically only used in long bone infections)
cefazolin/nafcillin/oxacillin is used when? when would vanc be used instead?
abx regimen for staph osteomyelitis
use vanc for MRSA or PCN allerg
levo/cipro + rifampin is used when? what are alternatives to this
PO abx that can be used for osteomyelitis after 2 weeks of IV abx.
alternatives are bactrim, doxy or clinda.
what suggests a persistent osteomyelitis infection
persistent elevation of ESR/CRP over 2 weeks of appropriate ABX
can lead to chronicity, pathological fracture, and impaired bone growth
complications of osteomyelitis
formation of cloaca, necrosis, sequestrum and involucrum are all associated with what condition
chronic osteomyelitis