Misc: Medical Marijuana Flashcards
The endocannabinoid system (ECS) affects what 5 things?
- sleep
- mood
- appetite
- memory
- bone growth
What are the 2 major cannabinoid receptors?
Where are they located in our nervous system?
- CB1: CNS
- CB2: PNS, immune cells
What is the main psychoactive compound in cannabis?
THC: delta-9-tetrahydrocannabinol
THC has primary activity on what receptor?
CB1
THC is metabolized by what cytochrome?
cytochrome P450
What is marinol (dronabinol) and casamet (nabilone) used for?
nausea/vomiting from chemotherapy and appetite stimulant for AIDS related wasting syndrome
What is savitex (nabiximols) used for?
symptomatic relief from MS and analgesia for cancer
What is CBD approved for?
epilepsy
What are the side effects of CBD?
- nausea, dry mouth, fatigue
What is the most important thing about edibles?
variable onset times
“suggest start low, go slow”
You should wait at least ____ hours before driving or operating heavy machinery.
4 hours
If using edibles, start with a small dose of _____ mg THC and wait an hour before consuming more.
10-25 mg
The highest % of use disorder in the past year was in what age group?
18-25 yo
T/F: Marijuana addiction is possible, though not as common as other legalized substances, and riskier the younger someone is when they start
True
Genetic disposition to ___________ is associated with an increased risk of cannabis use.
schizophrenia
What is the adverse effect of marijuana on patient’s with bipolar disorder?
may increase manic symptoms
some association between suicide attemp
Holding long pulls of a joint or hit is associated with what respiratory problem?
pneumothorax
What is the acute change in HR and BP with marijuana use?
increase HR and BP d/t sympathetic NS activation
There is an increase in MI risk with marijuana use in what age group?
<50
Cyclic vomiting and abdominal pain after marijuana use is consistent with what diagnosis?
marijuana hyperemesis syndrome
What patient qualifies for medical cannabis in MA?
A MA resident 18 years of age or older who has been diagnosed by a Certifying Healthcare Provider as having a debilitating medical condition
What is the medical cannabis limit in MA?
10 oz of cannabis / 60 days
What is the risk of driving with marijuana use?
2-3x increased risk of car crash
Roadside tests for marijuana cannot shown _____ someone used.
when
