Misc endocrine physiology Flashcards
1
Q
Effect of GH on insulin sensitivity
A
promotes insulin resistance
1
Q
Ghrelin produced where
A
stomach
3
Q
Effect of glucose on GH release
A
decreases it
4
Q
GH results in secretion of what?
A
IGF-1 (somatomedin C)
5
Q
Two effects of Ghrelin
A
stimulates hunger and GH release
6
Q
Effect of sleep loss of ghrelin and leptin
A
↑ ghrelin
↓ leptin
7
Q
ADH receptor function:
V1:
V2:
A
V1: blood pressure
V2: osmolarity
8
Q
ADH acts where in the kidney
A
aquaporin channel insertion in principal cells of renal collecting duct
9
Q
Wolff Chaikoff Effect refers to what?
A
Excess iodine inhibits iodine organification
Results in ↓ T3/T4 production
10
Q
Is most T3 synthesized in thyroid or target tissue
A
target tissue
11
Q
Thyroid hormones produced in what part of thyroid
A
Follicular cells
12
Q
What enzyme catalyzes T4 –> T3
A
5’-deiodinase
