Adrenal physiology Flashcards

1
Q

Effect of cortisol on insulin sensitivity

A

promotes resistance

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2
Q

Name the enzyme deficiency

elevated 17-hydroxyprogesterone

A

21-hydroxylase

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2
Q

Effect of cortisol on gluconeogenesis

A

↑ gluconeogenesis

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3
Q

17-alpha hydroxylase deficiency

Mineralocorticoids

Cortisol

Sex hormones

BP

[K]

A

Mineralocorticoids: ↑

Cortisol: ↓

Sex hormones: ↓

BP: ↑

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4
Q

Effect of cortisol on fibroblast activity

A

↓ fibroblast activity

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6
Q

21-hydroxylase deficiency

Mineralocorticoids

Cortisol

Sex hormones

BP

[K]

A

Mineralocorticoids: ↓

Cortisol: ↓

Sex hormones: ↑

BP: ↓

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7
Q

Name the enzyme deficiency

CAH XY pseudohermaphrodite

A

17alpha-hydroxylase deficiency

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8
Q

11-beta-hydroxylase deficiency

Mineralocorticoids

Cortisol

Sex hormones

BP

[K]

A

Mineralocorticoids:

Cortisol: ↓

Sex hormones: ↑

BP: ↑

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9
Q

Exogenous steroid use ID association

A

reactivation TB, candidiasis

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10
Q

Cortisol acts on what arteriole receptor

A

alpha-1

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11
Q

Effect of cortisol on osteoblast activity

A

↓ osteoblast activity

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