Adrenal physiology Flashcards
Effect of cortisol on insulin sensitivity
promotes resistance
Name the enzyme deficiency
elevated 17-hydroxyprogesterone
21-hydroxylase
Effect of cortisol on gluconeogenesis
↑ gluconeogenesis
17-alpha hydroxylase deficiency
Mineralocorticoids
Cortisol
Sex hormones
BP
[K]
Mineralocorticoids: ↑
Cortisol: ↓
Sex hormones: ↓
BP: ↑
Effect of cortisol on fibroblast activity
↓ fibroblast activity
21-hydroxylase deficiency
Mineralocorticoids
Cortisol
Sex hormones
BP
[K]
Mineralocorticoids: ↓
Cortisol: ↓
Sex hormones: ↑
BP: ↓
Name the enzyme deficiency
CAH XY pseudohermaphrodite
17alpha-hydroxylase deficiency
11-beta-hydroxylase deficiency
Mineralocorticoids
Cortisol
Sex hormones
BP
[K]
Mineralocorticoids:
Cortisol: ↓
Sex hormones: ↑
BP: ↑
Exogenous steroid use ID association
reactivation TB, candidiasis
Cortisol acts on what arteriole receptor
alpha-1
Effect of cortisol on osteoblast activity
↓ osteoblast activity