Misc. drugs

Question 1

Tamsulosin indication

Answer 1

Expulsion of kidney stones

BPH

Question 2

Tamsulosin mechanism of action

Answer 2

Ureteric wall contains α1 adrenergic receptors that mediate smooth muscle contraction. α-blockers relax ureteric wall

Question 3

What is the treatment for Onychomycosis?

Answer 3

Needs to be treated with oral antifungal agents – eg oral terbinafine for 3-6 months

Question 4

What two classes of drugs are used for chemical restraint in the case of acute agitation?

Answer 4

Benzodiazepines and neuroleptics

Question 5

To which class of drugs does Amlodipine belong?

Answer 5

Calcium channel blockers

Question 6

What are the two classes of Calcium channel blockers?

Answer 6

Dihydropyridines and non-dihydropyridines

Question 7

What is the action of the dihydropyridines?

Answer 7

Act mainly on arteriolar smooth muscle. Reduce cardiac contractility, heart rate and conduction.

Question 8

What is the difference between Diltiazem and verapamil?

Answer 8

Diltiazem has a greater effect on arteriolar smooth muscle than verapamil. Verapamil has a greater effect on cardiac contractility, heart rate and conduction.

Question 9

What is the mode of action of the dihydropyridines?

Answer 9

Act on arteriolar smooth muscle to reduce peripheral vascular resistance and BP. Minimal effect on myocardial cells.

Question 10

To which class of drugs does Tacrolimus belong?

Answer 10

Calcineurin inhibitors

Question 11

What are the indications for the calcineurin inhibitors?

Answer 11

Prevention and treatment of transplant rejection

Induction or maintenance of remission in immune and inflammatory diseases