misc drugs

Question 1

which targeted therapy for those with EGFR mutation in NSCLC?

Answer 1

gefitinib or erlotinib

Question 2

which targeted therapy for those with EML4-ALK mutation in NSCLC?

Answer 2

crizotinib

Question 3

Types of systemic targeted therapies for RCC (2)

Answer 3

VEGF pathway inhibitors (RTK inhibitors), or mTOR inhibitors

Question 4

Tx for non-muscle invasive urothelial carcinoma

Answer 4

Transurethral resection; if recurrent, intravesical therapy (BCG or mitomycin); if still unresponsive, cystectomy with urinary diversion

Question 5

Tx for muscle invasive urothelial carcinoma

Answer 5

If no metastasis, neoadjuvent chemotherapy, then cystectomy w/ urinary diversion; if metastatic, do chemo (gemcitabine/cisplatin), survival is 14mo if metastatic

Question 6

What is the methacholine challenge?

Answer 6

To measure airway responsiveness to Dx asthma