Misc. drugs Flashcards
Tamsulosin indication
Medical expulsive therapy for kidney stones
Tamsulosin mechanism of action
Ureteric wall contains α1 adrenergic receptors that mediate smooth muscle contraction. α-blockers relax ureteric wall
What is the treatment for Onychomycosis?
Needs to be treated with oral antifungal agents – eg oral terbinafine for 3-6 months
What is the treatment for tinea capitis?
Prolonged treatment (usually 2 months) with oral antifungals (Griseofulvin or terbinafine)
What two classes of drugs are used for chemical restraint in the case of acute agitation?
Benzodiazepines and neuroleptics
What are two types of Benzodiazepines commonly used for chemical sedation of acutely agitated patients?
Diazepam or Midazolam
What are two types of neuroleptics commonly used in chemical sedation?
Haloperidol or droperidol
What is the indication for moxonidine?
hypertension
What is the mechanism of action of moxonidine?
Centrally acting agonist at I1 imidazoline receptors and alpha2 adrenoreceptors, it reduces BP by reducing sympathetic tone.
To which class of drugs does Amlodipine belong?
Calcium channel blockers
What are the two classes of Calcium channel blockers?
Dihydropyridines and non-dihydropyridines
What is the action of the dihydropyridines?
Act mainly on arteriolar smooth muscle. Reduce cardiac contractility, heart rate and conduction.
What are two examples of dihydropyridines?
Verapamil and Diltiazem.
What is the difference between Diltiazem and verapamil?
Diltiazem has a greater effect on arteriolar smooth muscle than verapamil. Verapamil has a greater effect on cardiac contractility, heart rate and conduction.
What is the mode of action of the dihydropyridines?
Act on arteriolar smooth muscle to reduce peripheral vascular resistance and BP. Minimal effect on myocardial cells.
