Misc Flashcards
Meropenem
Carbapenem
1g IVPB q 8hrs
ID consult - gram negatives
Resistance from KPC and NDM
Vancomycin
15-20mg/kg IVPB q 8-12hrs
Staph
Check serum level before 5th dose, should be between 15-40mcg/dL
Ciprofloxacin
Fluoroquinalone
500mg oral q 12hrs 3 days
UTI gram negative
Levofloxacin
Fluoroquinalone
500mg oral q 24hrs 7-14 days
CA-PNA gram positive
Can switch from IV p one dose
Moxifloxacin
Fluoroquinalone
400mg oral
CA-PNA
Fluoroquinalone side effects
QTc elongation
Tendonitis
Erythromycin
Macrolide
500mg oral q 6hrs
URI
Biliary excretion
Azithromycin
Macrolide
500mg oral q 24hrs
CA-PNA
Biliary excretion
Macrolide side effects
Eryth: QT prolongation, motalin
Azith: cardiac risk
Gentamicin
Aminoglycoside
1.3-1.7mg/kg IVPB q 8hrs
Meningitis
Tobramycin
Aminoglycoside
1.3-1.7mg/kg IVPB q 8hrs
Pseudomonas
Neomycin
Aminoglycoside
Topical (or oral for GI sterilization)
Strep/staph
Aminoglycoside side effects
Check trough level if more than 3 days, if increasing, renal toxicity!
Ototoxicity: Gent-balance Neo-deafness Tobra-both Nephrotoxicity Neuromuscular blockade
Doxycycline
Tetracycline
100mg IVPB q 12hrs
Chlamydia
Liver adjust
Tigecycline
Tetracycline
100mg IVPB x 1 dose, then
50mg IVPB q 12hrs
ID consult, liver adjust
Tetracycline side effects
Photosensitivity
Bony structures
CNS
Resistance from efflux pump
Clindamycin
Lincosamide
300-450mg oral q 8hrs 5-10 days
Bacteroides
Trimethoprim/Sulfamethoxazole
Sulfonamide
160/800mg oral q 12hrs 3-5 days
UTI
Sulfonamide side effect
Dermatologic
Crystalluria
Acute hemolytic anemia
Necrosis of liver
Linezolid
Staph Hunter
600mg IV or oral q 12hrs 10-14 day
MRSA
Daptomycin
Staph Hunter
4mg/kg IVPB q 24hrs 7-14 days
MRSA
Staph Hunter side effects
Linezolid: thrombocytopenia, SSRI interactions
Daptomycin: eosinophilic PNA, myopathy (check CK-MM)