Minerals 03 17 2015 Flashcards

1
Q

What are the 9 essential minerals

A

Ms Mic Zic F

Magnesium
Selenium
Molybdenum
Iron
Copper
Zinc
Iodine
Chromium
Fluoride
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2
Q

Zinc

  1. function
  2. food sources
A

component of several enzymes

  • healing
  • sense of taste and smell
  • Proper function of immune system
  • growth and development during pregnancy, childhood, and adolescence

Food sources:

  • animal based foods: meat and seafood
  • plant based foods: nuts, beans, whole grains

*Fiber interferes with absorption of zinc

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3
Q

Zinc deficiencies

A
  • growth retardation
  • delayed sexual maturation
  • Acrodermatitis Enteropathica (well demarcated scaly plaques)
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4
Q

Zinc toxicities

A

Diarrhea, cramps, nausea, vomiting and decreased immune system function

  • high zinc interferes with copper absorption and metabolism
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5
Q

Acrodermatitis Enteropathica

A

autosomal recessive– zinc deficiency due to a transporter mutation (absorption deficit)

  • skin lesions, diarrhea, and alopecia (hair loss)
  • growth retardation
  • delayed sexual maturity
  • impaired immune system (fatal)
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6
Q

Copper

  • function
  • Foods
  • metabolism
A
  • part of number of enzymes in our body
  • regulation of neurotransmitters
  • important role in connective tissue formation
  • transport of iron
  • superoxidase dismutase– prevent oxidative damage to cells
  • cytochrome C oxidase – e- transport chain

Animal products: liver, shell fish
Plant products: seeds, legumes, cocoa, nuts

-copper and iron metabolism are linked

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7
Q

Copper deficiency (clinically)

A

-microytic anemia, neutropenia, leukopenia, low serum copper and ceruloplasmin

Signs/symptoms: anemia-related, myelopathy and peripheral neuropathy
*damages nerves

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8
Q

Cause of copper deficiency

A
  • bariatric and peptic ulcer surgery
  • malabsorption diseases
  • High Zn supplement ingesiton/ consumer products: denture crests, post 1982 pennies
  • unknown
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9
Q

Copper toxicitiy

A

Wilson disease

  • autosomal recessive disorder– no way to get rid of copper
  • brain and liver lesions
    tx: D- penicillamine or high doses of zinc is effective

Hemodialysis– high concentration of trace elements in contaminated dialysis fluids

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10
Q

Selenium

  • function
  • foods?
A
  • selenoproteins = antioxidants
  • immune systme
  • proper functioning of thyroid gland

Animal based food: Fish, meat
Plant based food:: whole grain products, nuts (Brazilian nuts have really high levels of selenium and should not be eaten regularly)

Selenium layers in soil

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11
Q

Selenium deficiency

A

Keshan disease
- heart disease characterized by cardiac tissue becoming fibrous– restrictive heart

  • may also be associated with certain cancers and thyroid hormone metabolism
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12
Q

Selenium toxicity

A

nausea, diarrhea, fatigue, irritability, hair loss, brittleness of nails, skin rashes, GARLIC BREATH

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13
Q

Iodine

  • function
  • foods?
A
  • proper functioning of thyroid and production of thyroid hormones
    • cell metabolism, regulation of basal energy expenditure, macronutrient metabolism, growth and organ maturation

Foods: seafood, bread, dairy products, plants growing iodine rich soil/ animals fed with these plants, salt

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14
Q

Iodine deficiency

A
  1. impaired growth
  2. mental retardation
  3. goiter
  4. increase risk of thyroid cancer– follicular cancer
  5. Cretinism: fetus has low birthweight and neurological disorders, (child:)severe mental retardation, short stature,
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15
Q

Iodine toxicity

A

Possibly increase risk of papillary cancer

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16
Q

Iron

  • function
  • foods?
A
  • Hemoglobin (RBCs)
  • Myoglobin
  • Cytochromes
  • provide energy to cells to perform work

Animal: meat, poultry, fish, and shellfish
Plant: nuts& seeds, legumes and beans, green leafy beg tables, raisins, whole grains and fortified cereals.

17
Q

iron deficiency

A
  • FATIGUE
  • PICA (compulsive eating of nonfood items)
  • PAGOPHAGIA ( compulsive eating of ice)
  • PALLOR, PALE CONJUCTIVA and SPOON NAILS
  • MICROCYTIC ANMEIA – low hemoglobin
  • sensation of feeling cold
  • Reduced work capacity and exercise tolerance
  • Affect neurotransmitter function
  • Affect immunological and inflammatory defuses
18
Q

Iron that comes from heme vs. non heme

A

Heme: animal sources, highly absorbable, absorption least influenced by other dietary factors

Non- Heme: various factors affect absorption

19
Q

Iron Toxicity

A
  • nausea, vomiting, stomach irritation, diarrhea, impaired absorption minerals

Hemochromatosis – C282Y gene

  • too much iron accumulation can damage organs, liver, pancreas, and heart muscle and thyroid
  • excess GI Fe absorption
  • sxs: lethargy and abdominal pain, bronze skin