Mineralocorticoids - Adrenocortical Steroids Flashcards

15.6, 15.7

1
Q

Class - Aldosterone

A

Mineralocorticoid

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2
Q

MOA of Aldosterone (Modulation of Electrolyte and H2O balance via renal system)

A

Increases Na+ reabsorption in distal nephron/collecting ducts-> increased H2O reabsorption, K+ secretion, H+ secretion, and HCO3- generation

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3
Q

Adverse effects of adrenocorticosteroids (8)

A
  1. Adrenal suppression
  2. Fluid and electrolyte abnormalities
  3. Metabolic changes
  4. Edema
  5. HTN
  6. Osteoporosis
  7. Growth suppression in children
  8. Cataracts

***key differences between drugs based on structure***

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