Milestone in Pharmacy Flashcards
Ancient man learned from?
Ancient man learned from Instincts, from observation of birds and beasts.
What was the first soothing application before the Dawn?
Cold water, leaf, dirt, or mud was the first sooth application.
From beginnings as remote and simple as these
came the proud profession of Pharmacy. Its
development parallels that of man.
Pharmacy - Before the Dawn
Though the cavemen’s methods were?
Crude
But many of today’s medicines spring from…
Sources as simple and elementary as those which were within reach of early man.
By trial what happened to Caveman/Ancient Man?
By trial he learned which served him best. Eventually he applied his knowledge for the benefits of others.
The jewel of ancient Mesopotamia, often called the cradle of civilization, provides the earliest known record of practice of the art of the apothecary.
Babylon
Practitioners of healing of this era (about 2600 B.C.)
Priest, pharmacists and physician were all in one.
In Ancient Babylonia period where is medical texts were first recorded
Clay Tablets.
What does the clay tablets from Ancient Babylonia period contains?
Symptoms of illness, prescription and directions for compounding, and invocation to the gods.
The methods find counterpart in today’s modern pharmaceutical, medical, and
spiritual care of the sick
Pharmacy in Ancient Babylonian
Emperor who sought out and investigated the medicinal value
of several hundred herbs.
Shen Nung
According to legend, stems
from Shen Nung (about 2000 B.C.),
Pharmacy in Ancient China/Chinese Pharmacy
A textbook on 365 drugs and Chinese herbs written by the Emperor Shen-Nung (circa 2800 BC)
Pen T-Sao
He reputed to have tested many of them on himself, and to have written the first Pen T-Sao, or native herbal, recording 365 drugs. Still worshiped
by native Chinese drug guilds as their patron god.
Shen Nung
What did Shen Nung conceivably examined?
Herbs, barks and roots brought in from the fields, swamps and woods that are still recognized in Pharmacy today.
A chinese mathematical design symbolizing creation and life.
Pa Kua
Medicinal plants in Chinese Pharmacy 6 that was tuckled.
Podophyllum (Mayapple)
Rhubarb
Ginseng
Stramonium
Cinnamon bark
Ma huang or Ephedra
Egyptian medicine dates from about 2900 BC, best known and most important pharmaceutical record.
Days of Papyrus Ebers
Papyrus Ebers
A collection of 800 prescriptions, mentioning 700 drugs.
Pharmacy in ancient Egypt was conducted by two or more echelons:
The gatherer and preparers of
drugs, and “chiefs of fabrication,” or head pharmacists.
What period was ““House of
Life.”?
Days of Papyrus Ebers (Ancient Egypt)
In a setting such as this, the Papyrus Ebers might have been dictated to a scribe by a head
pharmacist as he directed compounding activities in the drug room.
House of Life (Papyrus Ebers)
Among the greatest early Greek philosophers and natural scientists, is called the “Father of Botany.”
Theoprastus/Theophrastus (300 B.C)
Theophrastus observations and writings deals with?
Medical qualities and peculiarities of herbs are unusually accurate, even in the light of present knowledge.
What did Theophrastus did to his group of students?
He lectured to groups of students who walked about him, learning of nature by observing her treasures at firsthand.
In the picture presented in the PPT what plant did Theophrastus hold and what plant was behind me?
Belladoma
Pomegranate blooms,
senna, and manuscript scrolls. Slabs of ivory, coated with
colored beeswax, served the students as “slates.”
Writing was cut into the surface with a stylus.
What are slates?
Slabs of Ivory coated with beeswax, served the students as “slates”.
The Royal Toxologist
Mithridates VI (About 100 B.C)
What did Mithridates VI did?
He battled Rome for a lifetime then he found time
to make not only the art of poisoning, but also the
art of preventing and counteracting poisoning,
subjects of intensive study.
The “guinea pigs” that Mithridates VI used on which to test poisons and antidotes.
Prisoners
A person who collects roots and herbs to make medicine.
Rhizotomist/Herbalist
Visualize the picture in the PPT of Mithridates VI what is behind him and at lower right is?
Behind him is Rhizotomist offering fresh flowering aconite, ginger, and gentian – a two piece forerunner of the
champagne bucket.
What is Mithridates famed formula alleged panantidotal powers and was popular for over a thousand years?
Mithridatum
An early “trademarked” drug
Terra Segillata (Sealed Earth)
What is Terra Segillata (Sealed Earth)
One of the first therapeutic agents to bear such a mark was and a clay tablet.
Terra Segillata originated from?
Mediterranean island of
Lemnos before 500 BC.
Man learned early of the prestigious advantage of
trademarks as a means of identification of source
and of gaining customers’ confidence.
Terra Segillata
(Terra Segillata) One day each year clay was dug from? and in the presence of?
Lemnian Hillside in the presence of Governmental and Religious dignitaries
(Terra Sigillata) Washed, refined, rolled to a mass of proper thickness, the clay was formed into? and official seal by?
Pastilles, seal by priestesses, then sun-dried
Sealed Earth
Terra Sigillata
A scientist look at drugs
Pedanius Dioscorides
Contributed mightily to such a transition in
Pharmacy. In order to study materia medica,
Dioscorides accompanied the Roman armies
throughout the known world.
Pedanius Dioscorides
What did Pedanius Dioscorides? He record…
He recorded what he observed, promulgated
excellent rules for collection of drugs, their
storage and use.
Dioscorides text were considere as in 16th century?
Basic Science
Experimenter in Drug Compounding
Claudius Galenus (Galen 130-200 A.D)
Who’s the men of ancient times whose names are known and revered among both the professions
of Pharmacy and Medicine
Claudius Galenus (Galen 130-200 A.D)
Where did Galen practiced and taught Pharmacy and Medicine?
Rome
Galen principles of preparing and compounding medicines ruled in? for how many years?
Western world for 1,500 years.
A medicine made of natural rather than synthetic components.
Examples:
Galenicals
Semi-mythical remedy with as many as 65 ingredients, used as an antidote for poisoning,
Mithridatum
Galen was the originator of this emulsion of water and certain fats, usually including beeswax and various scent agents, designed to smooth skin and remove makeup.
Cold Cream
Pharmacy Patron Saints
Damian and Cosmas
Damian and Cosmas twin careers were cut short by? in what year?
Martyrdom in 303
What were built in their honor of Damian and Cosmas in Rome and other cities?
Churches
During the Middle Ages remnants of the Western knowledge of Pharmacy and Medicine were preserved in the monasteries (fifth to twelfth centuries).
Monastic Pharmacy
What did the Monks gathered in Monastic period of Pharmacy?
The monks gathered herbs and simples in the
field, or raised them in their own herb gardens.
In this era gardens were prominent to raise herbs?
Monastic Pharmacy
Who separated the art of Apothecary and Physician?
The Arabs
Where and when was first drug store established?
In Bagdad late in 8th century.
What did the Arabs preserved? and added? developing with the aid of
their natural resources syrups, confections,
conserves, distilled waters and alcoholic liquids.
They preserved Greco-Roman wisdom, added to it, developing with the aid of their natural resources syrups, confections, conserves, distilled waters and alcoholic liquids.
What milestone was the Arabs separated the arts of apothecary and physician, establishing in Bagdad late in the eighth century the first privately owned drug stores.
The First Apothecary Shop
The apothecary is examining logs of? indulge their taste for sweets with?
Sandalwood, Stalks of Sugar Cane
Among the brilliant contributors to the sciences of Pharmacy and Medicine during the Arabian era was one genius who seems to stand for his time the Persian (about 980-1037 A.D.), called?
Ibn Sina/Avicenna
What was Ibn Sina/Avicenna profession?
Pharmacists, poet, philosopher, physicianand diplomat who is an intellectual giant.
He was the favorite of Persian princes and rulers, the Persian Galen.
Ibn Sina/Avicenna
In European countries exposed to Arabian
influence, public pharmacies began to appear in
the 17th century. However, it was not until about
1240 A.D. that, in Sicily and southern Italy, what had happened?
Pharmacy was separated from Medicine
Where and when was Pharmacy and Medicine separated?
In Sicily Italy, and southern italy on 1240 A.D
In European countries exposed to Arabian
influence, public pharmacies began to appear in what century?
17th century
He was the Emperor of Germany as well as King of Sicily, was a living link between Oriental and Occidental worlds.
Frederick II of Hohenstaufen
What happened in King Frederick II Hohenstaufen’s palace?
He presented subject Pharmacists with the first European edict completely separating their responsibilities from those of Medicine, and prescribing regulations for their professional practice.
The idea of a pharmacopoeia with official status, to be followed by all apothecaries, originated in?
Florence
It was originally written in Italian and published that became the leagl standard forthe city in 1498.
Nuovo Receptario
One of the earliest manifestations of constructive interprofessional relations.
The collaboration between the guild of apothecaries and medical society.
The professional groups received official advice and guidance from who?
The powerful dominican monk, savonarola. who, at the time, was the political leader in Florence.
Trade in drug and spices was lucrative in what age?
Middle Ages
The drugs and spices was monopolized by what guild?
Guild of Grocers
Who was flanked by two beefeaters?
King James I
The period where Pharmacy, with its heritage of 50 centuries of service to mankind, has come to be recognized as of the great professions. Like Medicine, it has come through many revolutions, has learned many things, had to discard many of its older ways.
Pharmacy Today and Tomorrow
This are the professionals who are among the community’s finest educated people
Pharmacists
(Pharmacy Today and Tomorrow)
Who persuaded King James I to not punish the beefeaters?
Francis Bacon
(The Society of Apothecaries in London)
Instead of punishment, what did King James I granted?
Charter in 1617