Migraine

Question 1

Natural products

Answer 1

Caffeine

Question 2

Acute Txt

Answer 2

Excedrin Migraine (ASA, APAP, caff)
Aleve (Naproxen)

Question 3

women w/ Migraine + Aura

Answer 3

Are a higher risk for stroke and should not use estrogen-containing contraceptives

Question 4

Triptans

MOA, C/I

Answer 4

are selective for serotonin (5HT1) causing vasocontriction. Are 1st line for acute.

C/I: Stroke TIA, uncontrolled HTN, Ischemic heart disease or use within 24 hrs of another triptan.

Triptan sensation - Heavy Chest, Pressure in neck

Question 5

Sumatriptan

Answer 5

Brand: Imitrex, STATdose, Onzetra, Zembrance Treximet ( +Naproxen)

Question 6

Zolmitriptan

Answer 6

Zomig

Question 7

Rizatriptan

Answer 7

Maxalt, MAxalt- MLT

Question 8

Ergotamine Drugs

MOA, C/I, Use

Answer 8

MOA: Nonselective agonist of the serotonin receptor.

C/I in patients who did not receive benefit with triptans

Use: Next in line after triptan

Question 9

Dihydroergotamine

Brand: BBW, C/I

Answer 9

D.H.E. 45, Migranal
BBW: AVOID CYP3A4 INHIBITORS
C/I: same as triptans

Question 10

Ergotamine + Caffeine

Answer 10

Cafergot, Migergot

Question 11

Prophylactic TXT

Answer 11

If pt has 2 or acute attacks/week or more than 3/month

Or if it decreases quality of life.

Question 12

Beta Blockers

Use, which ones,

Answer 12

Propranolol (Inderal LA) (Lipophillic)
Timolol
Metoprolol (Lopressor, Toprol XL)

Question 13

AEDs

Answer 13

Valproic Acid (BBW: Liver, pancreatits, Teratogenic)

Topiramate (Trokendi XR, Topiramate) weight loss, cognitive impairment, metabolic acidosis, paresthesia.

Question 14

Rebound Headache

Answer 14

Limit acute TXT to 2 to 3 times per week. stop over used medication