Mieloma Multiple Flashcards

1
Q

Acronimo CRAB?

A

Ca. (hipercalcemia)
RENAL. (daño renal)
ANEMIA
BONE. (lesiones liticas)

Infecciones

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2
Q

Fisiopatologia del Mieloma multiple?

A

Neoplasia de cel plasmaticas (cel B) con produccion exesiva de inmunoglobulinas IgG, IgA y Bence jones

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3
Q

Criterios para mieloma multiple?

A

Mayores;
Proteina IgG >3.5g/dl IgA>2g/dl
Plasmocitosis medular >30%
Plasmocitoma

Menores
Lesiones liticas

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4
Q

Escala usada en mieloma multiple?

A

Durie - salmon y ISS

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5
Q

Tratamiento del MM?

A

1° linea es transplante en <70 años
+ 2 quimioterapia

No se transplanta >70 años
+3 quimioterapia (con melfalan)

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