Midterms [Lesson 1 & Prep. 1-10] Flashcards

1
Q

A substance, other than food, that alters the functions of the body

A

DRUG

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2
Q

It is used for the diagnosis, prevention, alleviation, and mitigation of diseases.

A

DRUG

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3
Q

Drug is used for _ _ _ _

A

DPAM: Diagnosis, Prevention, Alleviation, Mitigation of diseases

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4
Q

Drug substance; is responsible for the pharmacological action or drug effect.

A

ACTIVE PHARMACEUTICAL INGREDIENT (API)

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5
Q

Drug products/Final Product; The “drug carrier” used to deliver the API to the body

A

DOSAGE FORM or DRUG DELIVERY SYSTEM

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6
Q

Liberation; drug products must first be released from the dosage form in the process known as liberation.

A

PHARMACEUTICAL PHASE

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7
Q

The processes the dissolved drug product undergoes;
“what the body does to the drug

A

PHARMACOKINETIC PHASE

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8
Q

Manifested by the drug effect/ interaction between the drug and the specific receptor; “what the drug does to the body”

A

PHARMACODYNAMIC PHASE

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9
Q

refers to the breaking down of solid pharmaceutical substances, like tablets, into smaller particles or granules to increase its solubility.

A

DISINTEGRATION

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10
Q

the process of breaking down and dissolving a substance, whether in liquid, gaseous, or solid form, into a solvent

A

DISSOLUTION

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11
Q

this refers to the process of the movement of the drug from the initial site of administration towards and into the bloodstream.

A

ABSORPTION

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12
Q

the process of breaking down the drug and its chemical modification in the body.

A

METABOLISM

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13
Q

the movement of the drug from the bloodstream towards the tissues of the body or the site of action (e.g., brain).

A

DISTRIBUTION

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14
Q

the removal of drugs from the body, either as a metabolite or unchanged drug

A

EXCRETION

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15
Q

is the process of preparing or mixing a practitioner’s prescription or drug order.

A

PHARMACY COMPOUNDING

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16
Q

is the production and promotion of drug products’ resale in pharmacies.

A

MANUFACTURING

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17
Q

are homogenous mixtures made of solutes and its solvent (vehicle).

A

SOLUTIONS

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18
Q

the vehicle in which the solute is carried in solution.

A

SOLVENT

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19
Q

Solutions where water is used as solvent

A

Aqueous Solution - prone to degradation like molds/microorganisms

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20
Q

Solutions where oil is used as solvent

A

Oleaginous Solution - prone to oxidation

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21
Q

component in a solution, dissolved in the solvent

A

SOLUTE

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22
Q

may be solid (such as NaCl), liquid (such as ethyl alcohol solution) or gas (such as hydrochloric acid)

A

SOLUTE

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23
Q

An oral means of administration; The most common and compliant route of drug administration

A

PERORAL

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24
Q

An administration route wherein the drug is administered into the systemic circulation through the veins

A

INTRAVENOUS

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25
An administration route wherein the drug is administered into the systemic circulation through the airways
INHALATION
26
hard compressed pill that is composed entirely of medication
TABLETS
27
a dosage form that consists of an outer shell that encapsulates the powder or liquid medication
CAPSULES
28
a dosage form that consists of finely granulated solid particles of a medication
POWDERS
29
a dosage form that is a homogeneous liquid, consisting of solute/s mixed entirely and evenly dispersed in a solvent
SOLUTIONS
30
a monophasic liquid dosage form that can be aqueous or alcohol based and contains sugar
SYRUPS
31
a mixture that contains insoluble solid particles suspended in liquid media and is usually water based
SUSPENSIONS
32
oily semi solid substances that is applied to the affected area of the skin, healing and soothing various skin problems
OINTMENTS
33
water soluble semi solid substances applied to the skin
CREAM
34
dosage form that is composed of substances that dissolve at body temperature and is inserted into the rectum or vagina
SUPPOSITORIES
35
stirring a mixture to dissolve solid materials
AGITATION
36
a filtration process where large solid particles are allowed to settle at the bottom of a container and then pouring off the supernatant liquid carefully without disturbing the decanted particles
DECANTATION
37
the process of removing solid particles in a mixture to obtain a clear, homogeneous preparation. This is carried out using mechanical filtering media (e.g. filter paper) or filtration aids (e.g. talc).
FILTRATION
38
mixing the components of a semi-solid preparation with the aid of gentle heat
FUSION
39
the process of reducing the particle size of solid ingredients by addition of a levigating agent (a liquid) and grinding with mortar and pestle into a smooth powder
LEVIGATION
40
passing of a suitable solvent through a drug substance to extract a soluble component
PERCOLATION
41
the addition of enough solvent to make up for the volume required in the prescription
Q.S. ADD
42
is the process of adding all ingredients and mixing well
SIMPLE ADMIXTURE
43
the process of reducing substances to fine particles by grinding in a mortar and pestle. This process also effectively mixing solid ingredients with perfume oils
TRITURATION
44
using stirring as a means of agitating and affecting dissolution of the solute into the solvent
SIMPLE SOLUTION or ADMIXTURE
45
What are the four (4) drug phases in drug action?
Drug product > Pharmaceutical phase > Pharmacokinetic phase > Pharmacodynamic phase
46
What are the general steps in compounding process?
PCFC: Preparing, Compounding, Final checking, Cleaning
47
Compounding Techniques in compounding a solution
1. Use of cosolvent or solubilizing agent 2. Application of heat 3. Reduction of particle size 4. Vigorous agitation
48
SOLUTIONS ARE EXPRESSED IN TERMS OF % STRENGTHS
1. Percent weight-by-weight (%w/w) - solid preparation (solid active ingredient and solid vehicles or solvent) 2. Percent weight-by-volume (%w/v) - liquid preparation (solid or gas active ingredient and liquid vehicle or solvent) 3. Percent volume-by-volume (%v/v) -liquid preparation (liquid active ingredient and liquid vehicle or solvent)
49
COLD
2-8℃ // 36-46°F
50
COOL
8-15℃ // 46-59°F
51
ROOM TEMP
20-25℃ // 68-77°F
52
WARM
30-40℃ // 86-104°F
53
EXCESSIVE HEAT
Above 40℃ // Above 104°F
54
FREEZER
-25 to -10 ℃ // -13 to -14°F
55
Appearance clear, homogeneous, odorless Synonym: Hydrogen borate, Boron hydroxide, Boracic acid Compounding: Boric acid: 3g Purified water: 21 ml + 39 ml
BORIC ACID SOLUTION, NF
56
Method of preparation of Boric acid
Agitation/ Simple Admixture
57
Boric acid concentration as eyewash
0.02%
58
Appearance: Clear, earthy smell, bitter taste Synonym: Slaked lime Compounding: Calcium hydroxide: 0.2g Purified water: 60 ml USES: Topical medical salve, Gastric preparation, dental filling agent, PH buffer and neutralizer
CALCIUM HYDROXIDE, USP
59
CALCIUM HYDROXIDE, USP turns into _______ ________ WHEN EXPOSED TO AIR
Insoluble carbonate
60
Appearance: Clear, Pungent/Marker-like smell Synonym: Orthohydroxybenzioc acid Compounding: Salicylic acid: 6g Alcohol: 24 ml + 36 ml USES: Kerytolic, Treats acne, dandruff, calluses, corn, warts
SALICYLIC ACID SOLUTION, 10%
61
Chemical classification of SALICYLIC ACID SOLUTION, 10%
Beta hydroxy acid (BHA)
62
Appearance: Brown-orange, faint iodine smell STARCH TEST: bluish-purple Synonym: Lugol’s Solution Compounding: Iodine: 3g Potassium Iodide: 6g Purified water: 60 ml USES: Overactive thyroid, iodine deficiency, antiseptic
STRONG IODINE SOLUTION, USP
63
Appearance: Clear, Salty smell Compounding: Sodium Chloride: 0.5g Potassium Chloride: 0.1g Calcium Chloride: 0.1g Purified water (Boiled): 60ml USES: Intravenous solution; Dehydration, Flow of IV medication, Restoring fluid, Keeping an IV catheter open
RINGER’S SOLUTION, NF
64
This is not for parenteral administration
RINGER’S SOLUTION, NF
65
Appearance: Golden-brown, Lysol/bleach smell Compounding: Boric acid: 1.5g Thymol: 0.03g Chlorothymol: 0.03g Menthol: 0.03g Eucalyptol: 0.01ml Methyl salicylate: 0.01ml Thyme oil: 0.001ml Alcohol: 18ml Purified water: 60ml USES: Antiseptic
ANTISEPTIC SOLUTION, NF
66
ANTISEPTIC SOLUTION, NF Responsible for Antiseptic action
Boric acid
67
ANTISEPTIC SOLUTION, NF Serves as filtering aid
Talc
68
ANTISEPTIC SOLUTION, NF Aids in solubilization of volatile substances
Alcohol
69
Thyme Oil
Thyme (Mint family/ Lamiaceae)
70
Eucalyptus Oil
Eucalyptus Leaf (Myrtle family/ Myrtaceae)
71
Menthol
Peppermint (Lamiaceae)
72
Methyl Salicylate
Wintergreen Leaf (Heath family/ Ericaceae)
73
Thymol
Thyme (Mint family/ Lamiaceae)
74
Thyme
Thyme (Mint family/ Lamiaceae)
75
Compounding: Potassium bicarbonate: 1.2g Sodium borate: 1.2g Thymol: 0.03g Eucalyptol: 0.06 ml Methyl salicylate: 0.03g Amaranth solution: 0.84 ml Alcohol: 3 ml Glycerin: 6 ml Purified water: 60 ml USES: to rinse your teeth, gums, and mouth. It usually contains an antiseptic to kill harmful bacteria that can live between your teeth and on your tongue
MOUTHWASH, NF
76
Bad breath
Halitosis
77
Treats throat infections
Gargle
78
Colorant (red)
Amaranth solution
79
Synonym: Citrate of Magnesia Compounding: Magnesium carbonate: 2.6g Citric acid (anhydrous): 4.2g Syrup: 10.3g Talc: 0.86g Lemon oil: 0.017 ml Potassium bicarbonate: 0.43g Purified water: 60 ml USES: Saline laxative, treats constipation
MAGNESIUM CITRATE SOLUTION, USP
80
MAGNESIUM CITRATE SOLUTION, USP Enhances physical properties of Magnesium carbonate
Citric acid
81
MAGNESIUM CITRATE SOLUTION, USP Makes solution palatable and effective
Syrup and Potassium bicarbonate
82
Appearance: Whitish color, Vinegar smell Synonym: Burow’s Solution (FROM KARL AUGUST BUROW) Compounding: Aluminum sulfate: 5.2g Lead acetate: 9g Purified water: 60 ml USES: Topical astringent; Treats inflammation, stinging, and heals skin
ALUMINUM ACETATE SOLUTION, USP
83
stops/ slows microorganism growth
Antiseptic
84
Causes skin contraction, shrinkage, and drying of oils from skin
Astringent
85
Appearance: Orange color, Pungent smell Synonym: Vlemnickx’s Solution Compounding: Lime: 9.9g Sublimed sulfur: 15g Purified water: 60 ml USES: Treats ringworm infection, scabies, pediculosis
SULFURATED LIME SOLUTION, NF
86
Chemical composition of SULFURATED LIME SOLUTION, NF
CaO
87
Active ingredients present when sulfur reacts with lime
Calcium pentasulfide (2CaS5) and Calcium thiosulfate (CaS2O3)
88
Plant insecticide
20% concentration SULFURATED LIME SOLUTION, NF