Midterm Review Flashcards
1
Q
What is a lactam?
A
cyclic amide
2
Q
What is a lactone?
A
cyclic ester
3
Q
σx
A
- negative for EDGs
- positive for EWGs
4
Q
What are rotatable bonds?
A
any single bond (sigma bond) not in a ring bound to an internal non-hydrogen atom
5
Q
EDG
A
- negative σx
- pKa increases (from parent to substituent)
6
Q
EWG
A
- positive σx
- pKa decreases (from parent to substituent)
