midterm review Flashcards

1
Q

What are the 10 most common addictions?

A

→ Alcohol
→ Smoking
→ Drug
→ Gambling
→ Food
→ Video Games
→ Internet
→ Sex
→ Shopping
→ Work

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2
Q

At about what periods in history did cocaine reach its first and second peaks of popularity, and when was amphetamine’s popularity at its highest

A

→ Cocaine : 1890’s and 1980’s

→ Amphetamines : 1960’s

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3
Q

How did Mariani, Halsted, and Freud popularize the use of cocaine?

A

→ Importing coca leaves and extracting it into products.

→ Experimenting with the ability of cocaine to produce local anesthesia.

→ Using it for treatment of depression and morphine addiction.

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4
Q

How are coca paste, freebase, and crack similar?

A

They’re all the same. Are all made from the coca plant and are a form of cocaine.

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5
Q

Following cocaine use, how long does it take for the drug (or its metabolites) to be eliminated from the body and not detected in the urine?

A

Two to three days after the last dose.

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6
Q

What similarities and what differences are there in the toxic effects of cocaine and amphetamine?

A

→ Similarity: Extended use leads to paranoia.

→ Toxicity of Cocaine: no evidence that occasional use of small amounts is a threat to health but doses can be increased to point of toxicity.

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7
Q

How would medical practice be affected if both cocaine and amphetamine were placed on Schedule I?

A

Cocaine would not be able to be used as local anesthesia and amphetamine would not be used for ADHD.

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8
Q

How does the chemical difference between methamphetamine and amphetamine relate to the behavioral effects of the two drugs?

A

→ Amphetamines are still used today as an adjunctive therapy to treat depression.

→ Methamphetamine: Is more potent so it takes less to get a greater effect.

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9
Q

Compare the dependence potential of cocaine with that of amphetamine.

A

You can be addicted to both if you use it enough. They are rarely used because they have a high potential of addiction. They have a high potency of addiction and must be measured carefully.

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10
Q

Describe the effects of amphetamines on mental performance.

A

Reduces activity levels and improves concentration in hyperactive children and adults.

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11
Q

Give two examples of anxiety disorder.

A

→ Social Anxiety Disorder

→ Panic Disorder

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12
Q

Is schizophrenia a functional or an organic psychosis?

A

Functional.

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13
Q

Besides sadness, what are some other indicators of a major depressive episode?

A

→ Significant changes in body weight or appetite (increased or decreased).

→ Markedly diminished interest or pleasure in most activities.

→ Diminished ability to think or concentrate.

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14
Q

What type of drug is chlorpromazine, and where was it first tested on patients?

A

An antipsychotic first tested in France for patients of surgery.

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15
Q

What is tardive dyskinesia, and how does it respond to a reduction in the dose of an antipsychotic drug?

A

Most serious complication of antipsychotic drug treatment after reduction. Rhythmic, repetitive sucking and smacking movements of the lips; thrusting of the tongue in and out (“fly-catching”); and movements of the arms, toes, or fingers. Happens when someone is not weened off the drug.

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16
Q

Which type of drug was discovered while testing an antituberculosis agent?

A

(MAO) Monoamine oxidase inhibitor.

17
Q

How do the selective reuptake inhibitors differ from the older tricyclics in terms of their actions in the brain?

A

Newer drugs have fewer other actions than the tricyclics, referred to as SSNRIs.

18
Q

What were two of the three reasons it took so long for lithium to be available for use in the United States?

A

1: Salt-substitute poisonings.

2: Mania was not seen as a major problem in the United States.

3: Economically, the US companies had trouble introducing them to make a profit.

19
Q

If clozapine is so dangerous, why is it prescribed at all?

A

To lower white blood count. The drug was made available again as long as patients had periodic blood samples taken to monitor their white cells.

20
Q

Why was Prozac the most widely prescribed antidepressant drug ever marketed?

A

Prozac is safer than the tricyclic antidepressants because it is less likely to lead to overdose deaths.