Midterm Flashcards
How are all vertebrate brains organized?
In two hemispheres
Only vertebrates have what particular nervous system components?
Both a CNS and PNS
What are the three main components of the prototypical neuron?
- Dendrites
- Cell body/soma
- Axon(s)
Neurons are far outnumbered by what kind of cell?
Glia
What is currently the most common type of structural neuroimaging in humans?
MRIs
What method of structural neuroimaging is best for visualization of groups of axons?
DTI
The DTI method of structural neuroimaging is particularly useful in what cases?
- Diffuse brain injury
- Multiple sclerosis
Explain the physical differences between rats housed in enriched environments versus those housed in laboratory environments
- Enriched environment rats have cortical neurons with more and longer dendrites
- Enriched environment rats have dendrites with more connections with other neurons
What physical difference was noted among taxi drivers in the London taxi driver study?
When compared to average Londoners, the taxi drivers had slightly larger hippocampal volumes
What are the two distinct types of nerve fibres connecting the muscles to the spinal cord?
- Sensory (PNS to spinal cord)
- Motor (spinal cord to muscles)
Most sensory inputs enter the brain through what structure?
Thalamus
Where is the A1 located?
Temporal lobe
Where is the S1 located?
Parietal lobe
Where is the V1 located?
Occipital lobe
Where is the M1 located?
Frontal lobe
The primary auditory cortex (A1) is responsible for what?
Sounds
The primary somatosensory cortex (S1) is responsible for what?
Sensations from skin and internal organs
The primary visual cortex (V1) is responsible for what?
Sight
The primary motor cortex (M1) is responsible for what?
Coordinated movement
Most synapses are formed between what?
The axon of a presynaptic neuron and the dendrite of a postsynaptic neuron
Neurotransmitters are kept where?
At the end of the presynaptic axon in vesicles
Functional neuroimaging studies typically examine what?
How blood flow in a particular brain area changes depending on what the person is doing or thinking
Which method of functional neuroimaging has better temporal precision, but worse spatial precision?
Electroencephalography (EEG)
What American psychologist spent time researching the engram?
Karl Lashley
Drugs can affect the brain in what ways?
- Neurotransmitter release
- Activation of postsynaptic receptors
- Neurotransmitter inactivation
- Neurotransmitter reuptake
Hebbian learning may also be referred to in what way?
“Neurons that fire together, wire together”
Neuroscience
The study of the brain and the rest of the nervous system
Nervous system
An organism’s system of tissues specialized for distributing and processing information
Neuron
A type of cell that is specialized for information processing
Central nervous system (CNS)
The part of the vertebrate nervous system consisting of the brain and spinal cord
Peripheral nervous system (PNS)
The part of the nervous system that carries information from sensory receptors to the central nervous system and carries commands from the central nervous system to muscles
Cerebral cortex
The brain tissue covering the top and sides of the brain in most vertebrates
The cerebral cortex is involved in what?
Storage and processing of sensory inputs and motor outputs
The parietal lobe is important for what?
Processing somatosensory information
The temporal lobe is important for what?
- Language
- Auditory processing
- Learning new facts
- Forming new memories of events
Dendrite
Extension of a neuron that is specialized to receive signals from other neurons
Cell body/soma
The central part of the neuron that contains the nucleus and integrates signals from all the dendrites
Axon
The output extension of a neuron
Glia
A type of cell that provides functional or structural support to neurons
Structural neuroimaging
Techniques for creating images of anatomical structures within the living brain
Magnetic resonance imaging (MRI)
A method of structural neuroimaging based on recording changes in magnetic fields
Diffusion tensor imaging (DTI)
A type of MRI that measures the diffusion of water in brain tissue, permitting bundles of axons throughout the brain to be imaged
Enriched environment
An environment that provides sensory stimulation and opportunities to learn and explore
Reflex
An involuntary and automatic (unlearned) response
Synapse
A narrow gap between two neurons across which chemical messages can be transmitted
Presynaptic
On the sending side of the synapse
Postsynaptic
On the receiving side of the synapse
Receptor
A specialized molecule located on the surface of a neuron, to which one or more particular neurotransmitters can bind
Neuromodulator
A neurotransmitter that acts to modulate activity in a large number of neurons rather than in a single synapse
Positron emission tomography (PET)
A method of functional neuroimaging based on detecting radiation from the emission of subatomic particles called positrons, associated with the brain’s use of glucose from the blood
Functional magnetic resonance imaging (fMRI)
A method of functional neuroimaging based on comparing an MRI of the brain during performance of a task with an MRI of the brain at rest
Electroencephalography (EEG)
A method for measuring electrical activity in the brain by means of electrodes placed on the scalp
Event-related potential (ERP)
Electroencephalograms from a single individual averaged over multiple repetitions of an event
Neurophysiology
The study of the activity and function of neurons
Single-cell recording
Use of an implanted electrode to detect electrical activity in a single cell
Engram
A physical change in the brian that forms the basis of a memory
Theory of equipotentiality
The theory that memories are stored globally, by the brain as a whole, rather than in one particular brain area
Synaptic plasticity
The ability of synapses to change as a result of experience
Hebbian learning
The principle that learning involves strengthening the connections of coactive neurons
Long-term potentiation (LTP)
A processing which synaptic transmission becomes more effective as a result of recent activity
Long-term depression (LTD)
A process in which synaptic transmission becomes less effective as a result of recent activity
Reflex arc
Behaviours driven by interactions of the spinal cord and sensory receptors
What are the two divisions of declarative memory?
Semantic and Episodic
What are the two divisions of long term memory?
Declarative and Non-Declarative
What are the differences between declarative and non-declarative information?
- Flexibility
- Metamemory
- Required exposures
What led H.M. to seek brain surgery treatment?
Severe, debilitating epileptic seizures
What surgery was done for H.M.?
Bilateral Medial Temporal Lobectomy, removed both medial temporal lobes, including the hippocampus
Medial temporal lobes
The medial (or inner) surface of the temporal lobes that contain the hippocampus, the amygdala, and other structures important for memory
What happened as a result of H.M.’s surgery?
He developed anterograde amnesia
Episodic memory
Memory for specific autobiographical events; it includes info about the spatial and temporal contexts in which the event occurred
Semantic memory
Memory for facts or general knowledge about the world, including general personal info
What two key features do episodic and semantic memories share?
- Flexibility - can be communicated in a format different from that in which it was acquired
- Consciously accessible
Declarative memory
A broad class of memories, both semantic and episodic, that can be communicated in some way
Non-declarative memory
A broad class of memory that includes skill memory and other types of learning
Explicit memory
A category of memory that includes semantic memory and episodic memory and consists of memories of which the person is aware
Implicit memory
Memory that occurs without the learner’s awareness
Radial arm maze
A maze with a central area from which several arms branch off like the spokes of a wheel
What is the radial arm maze used to test?
To test semantic memory in non human animals
What was the BBC Radio study?
- BBC radio changed broadcast frequencies and saturated the airwaves with announcements
- Only a quarter of listeners who heard the announcements 25+ times per day for many weeks learned the new call numbers
The effect of background info on memory is limited to what process?
Encoding
Levels of processing effect
The finding that deeper processing leads to better recall of the info than shallow processing
What was the word list study of levels of processing?
- Subjects were shown a list of words, one at a time
- For some words, participants were asked to decide whether the word described something animate or inanimate
- For other words, they were asked to decide whether the first and last letter were in alphabetical order
- Participants later recognized the animate/inanimate words better
What is the criticism for levels of processing theory?
Too vague - how do we know if someone is or isn’t processing a word “deeply”?
Transfer-appropriate processing effect
The finding that memory retrieval is best when the cues available at testing are similar to those available at encoding